Evidence map›Paper›PMID 39448280›Full record

ArticleJournal of voice : official journal of the Voice Foundation2024

A Methodology to Quantify the Effective Vertical Thickness of Prephonatory Vocal Fold Medial Surface.

Sarah Lehoux, Zhaoyan Zhang

Abstract read
In one paragraph

Article in Journal of voice : official journal of the Voice Foundation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Sarah LehouxDepartment of Head and Neck Surgery, University of California, Los Angeles, Los Angeles, California.
Zhaoyan ZhangDepartment of Head and Neck Surgery, University of California, Los Angeles, Los Angeles, California. Electronic address: zyzhang@ucla.edu.

Funding

Laryngeal and vocal tract strategies to reduce vocal fold contact pressureR01DC020240 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHAOYAN ZHANG · 2023 to 2026
$2.5M
NIDCD NIH HHS R01 DC020240
6 · The paper itself

Abstract

objectiveThe shape of the vocal fold medial surface, particularly its vertical thickness, has been shown in computational and physical modeling studies to be highly influential in regulating glottal closure during phonation. However, because of the difficulty to quantify the vertical thickness in real vocal folds, this influence has often been overlooked in clinical contexts. Therefore, the goal of this study is to present a method to calculate an effective vertical thickness of the medial surface that is predictive of the glottal closure pattern during phonation.

methodsAn effective vertical thickness of the medial surface is calculated as a weighted integral of the medial surface contour along the vertical dimension. The weight is one for the part of the medial surface within a fixed threshold distance from the most medial point, and decays exponentially otherwise. The influence of the threshold distance value on the effective thickness value is investigated. Additionally, the sensitivity of the calculated effective thickness to slight misidentification of the vertical glottal midline is also studied. The methodology is validated on the vocal fold medial surface data from a canine hemilarynx at different levels of thyroarytenoid muscle activation.

resultsFor most threshold distances, the thickness follows an expected sigmoid-like trend with respect to the thyroarytenoid muscle activation level. A threshold distance of 0.05 mm appears optimal as it produced thickness changes in a range comparable to previous computational and experimental studies. The methodology is relatively robust to slight misidentification of the vertical glottal midline.

conclusionsA methodology to estimate the effective vocal fold vertical thickness from medial surface contours is proposed. The methodology can be applied in future studies to correlate medial surface shape to relevant parameters characterizing vocal fold vibration as well as clinical evaluation of treatment effectiveness.

Indexed as

Closed quotientComputed tomographyMagnetic resonance imagingMedial surfaceVertical thickness

Identifiers

PMID39448280
PMCPMC12014861

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.