Evidence map›Paper›PMID 39447571›Full record

ArticleCell2024

Mechanistic study of a low-power bacterial maintenance state using high-throughput electrochemistry.

John A Ciemniecki, Chia-Lun Ho, Richard D Horak, Akihiro Okamoto, Dianne K Newman

Abstract read
In one paragraph

Article in Cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Energetic gradients emerge in developing motor-microtubule structures.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Extracellular matrix chemistry tunes bacterial biofilm metabolism and optimizes fitness.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Review
  9. Review
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  11. Review
  12. Article
  13. Nitric oxide tunes secreted metabolite bioactivity.bioRxiv : the preprint server for biology · 2025
    Article
  14. Single-cell lysis patterns morphogenesis of eDNA in the matrix ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. bioRxiv : the preprint server for biology · 2025
    Article
  17. Decoding in-cell respiratory enzyme dynamics by label-free in situ electrochemistry.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John A CiemnieckiDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Chia-Lun HoResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, 1-1 Namiki, Tsukuba 305-0044, Ibaraki, Japan; School of Chemical Sciences and Engineering, Hokkaido University, 13 Kita, 8 Nishi, Kita-ku, Sapporo 060-8628, Hokkaido, Japan.
Richard D HorakDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Akihiro OkamotoResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, 1-1 Namiki, Tsukuba 305-0044, Ibaraki, Japan; Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan; School of Chemical Sciences and Engineering, Hokkaido University, 13 Kita, 8 Nishi, Kita-ku, Sapporo 060-8628, Hokkaido, Japan; Living Systems Materialogy (LiSM) Research Group, International Research Frontiers Initiative (IRFI), Tokyo Institute of Technology, Yokohama 226-8501, Kanagawa, Japan. Electronic address: okamoto.akihiro@nims.go.jp.
Dianne K NewmanDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Division of Geological & Planetary Sciences, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: dkn@caltech.edu.

Funding

Biological mechanisms and consequences of efficient extracellular electron transfer in Pseudomonas aeruginosaR01AI127850 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Dianne K Newman · 2017 to 2026
$5.6M
NIAID NIH HHS R01 AI127850
6 · The paper itself

Abstract

Mechanistic studies of life's lower metabolic limits have been limited due to a paucity of tractable experimental systems. Here, we show that redox-cycling of phenazine-1-carboxamide (PCN) by Pseudomonas aeruginosa supports cellular maintenance in the absence of growth with a low mass-specific metabolic rate of 8.7 × 10

Indexed as

Oxidation-ReductionPhenazinesPseudomonas aeruginosaAnti-Bacterial AgentsElectrochemical TechniquesEnergy MetabolismFermentationHigh-Throughput Screening AssaysAnti-Bacterial AgentsPhenazinesbacterial slow growthelectron shuttlingextracellular electron transferfacilitated fermentationlow-power metabolismmaintenance energyphenazinesPseudomonas aeruginosascreen-printed electrode

Identifiers

PMID39447571
PMCPMC11606744

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.