Evidence map›Paper›PMID 39447288›Full record

ArticleBurns : journal of the International Society for Burn Injuries2024

The treatment effect of operative intervention for flame versus scald burns in resource-limited settings.

Sarah Peiffer, Linda Kayange, Selena An, Olivia Boddie, Anthony Charles, Jared Gallaher

Abstract read
In one paragraph

Article in Burns : journal of the International Society for Burn Injuries, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah PeifferMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Linda KayangeKamuzu Central Hospital, Lilongwe, Malawi.
Selena AnDepartment of Surgery, University of North Carolina at Chapel Hill, NC, USA.
Olivia BoddieDepartment of Surgery, University of North Carolina at Chapel Hill, NC, USA.
Anthony CharlesDepartment of Surgery, University of North Carolina at Chapel Hill, NC, USA.
Jared GallaherDepartment of Surgery, University of North Carolina at Chapel Hill, NC, USA. Electronic address: jared_gallaher@med.unc.edu.

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
FIC NIH HHS D43 TW009340
6 · The paper itself

Abstract

introductionIn resource-limited environments, it is critical to triage burn patients most likely to benefit from operative intervention. This study sought to identify patients with a more significant treatment effect after operative intervention following burn injury at a tertiary burn center in Lilongwe, Malawi.

methodsThis is a retrospective analysis of burn patients presenting to Kamuzu Central Hospital from 2011 to November 2022. We compared patients based on whether they had scald or flame burns. Using logistic regression, we estimated the adjusted treatment effect of operative intervention on in-hospital mortality. Operative intervention was defined as burn excision and debridement with or without skin grafting.

resultsWe included 3266 patients. 2099 (64.7 %) patients had a scald burn, and 1144 (35.3 %) had a flame burn. 630 patients (19.3 %) underwent surgery. Crude mortality among all patients was 18.1 %, and for patients who underwent surgery, it was 9.7 %. When adjusted for total body surface area burned (TBSA) and age, the average treatment effect of surgery on mortality was - 0.07 (95 % CI - 0.11, - 0.033) for patients with scald burns and - 0.17 (95 % CI - 0.22, - 0.11) for patients with flame burns (Fig. 1). For patients with flame burns, the adjusted odds ratio of death associated with surgery was 0.26 (95 % CI 0.17, 0.39).

conclusionsOperative intervention confers a survival advantage for patients with flame burns, and the average treatment effect was more significant compared to patients with scald burns. In general, in resource-limited environments flame burns should be prioritized for surgery over scald burns to improve patient outcomes.

Indexed as

Body Surface AreaBurnsDebridementHospital MortalitySkin TransplantationAdolescentAdultBurn UnitsChildChild, PreschoolDeveloping CountriesFemaleHumansInfantLogistic ModelsMalawiBurn outcomesFlame burnsLow-resource settingsResource managementScald burnsSub-Saharan Africa

Identifiers

PMID39447288
PMCPMC11625598

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.