ArticleJournal of applied clinical medical physics2025
Dosimetric consequences of adapting the craniocaudal isocenter distance to daily patient position in craniospinal irradiation using volumetric modulated arc therapy.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Diurnal variation of the distance between cranium and the third lumbar vertebra and its implications for craniospinal irradiation.Physics and imaging in radiation oncology · 2025Article
- Dosimetric consequences of adapting the craniocaudal isocenter distance to daily patient position in craniospinal irradiation using volumetric modulated arc therapy.Journal of applied clinical medical physics · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
purposeIn craniospinal irradiation, two or three isocenter groups along the craniocaudal axis are required to cover the long treatment target. Adapting the isocenter distance according to daily deviations in patient position is challenging because dosimetric hot or cold spots may occur in the field junction. The aim of this study was to quantify the effect of adapting the isocenter distance to patient position on the dose distribution of the field overlap region in craniospinal irradiation using partial-arc volumetric modulated arc therapy.
methodsThe magnitude of isocenter distance deviations in craniocaudal direction was quantified by registering the setup images of 204 fractions of 12 patients to the planning images. The dosimetric effect of these deviations was determined by shifting the isocenters of the original treatment plan and calculating the resulting dose distribution.
resultsOn fraction-level, deviations larger than 3 mm caused more than 5 percentage point changes in the doses covering 2% (D
conclusionsCraniocaudal isocenter distance adaptation can be conducted provided that the mean isocenter distance deviation over the treatment course is within 3 mm.
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