Evidence map›Paper›PMID 39446940›Full record

ArticleScience (New York, N.Y.)2024

Soft hydrogel semiconductors with augmented biointeractive functions.

Yahao Dai, Shinya Wai, Pengju Li, Naisong Shan, Zhiqiang Cao, Yang Li, Yunfei Wang, Youdi Liu, Wei Liu, Kan Tang and 16 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Review
  3. Seamless biointerfaces in devices.Nature materials · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Multiscale Manufacturing of Organic Electronic Materials.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Tissue-bioelectronics interfaces.Chemical Society reviews · 2026
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Yahao DaiPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-6393-5514
Shinya WaiPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-8973-1923
Pengju LiPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-0327-4758
Naisong ShanPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-1476-6539
Zhiqiang CaoSchool of Polymer Science and Engineering, Center for Optoelectronic Materials and Devices, University of Southern Mississippi, Hattiesburg, MS 39406, USA.ORCID 0000-0002-4439-4414
Yang LiPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-1912-1438
Yunfei WangSchool of Polymer Science and Engineering, Center for Optoelectronic Materials and Devices, University of Southern Mississippi, Hattiesburg, MS 39406, USA.ORCID 0000-0001-7555-5308
Youdi LiuPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Wei LiuPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-1207-204X
Kan TangSchool of Polymer Science and Engineering, Center for Optoelectronic Materials and Devices, University of Southern Mississippi, Hattiesburg, MS 39406, USA.ORCID 0000-0003-0012-0224
Yuzi LiuCenter for Nanoscale Materials, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0002-8733-1683
Muchuan HuaCenter for Nanoscale Materials, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0003-3218-5591
Songsong LiPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9784-2877
Nan LiPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Shivani ChatterjiPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0009-0007-1399-4891
H Christopher FryCenter for Nanoscale Materials, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0001-8343-5189
Sean LeeDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Cheng ZhangPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-3026-1159
Max WeiresPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0009-0006-6568-3270
Sean SutyakPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Jiuyun ShiDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-1949-0348
Chenhui ZhuAdvanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.ORCID 0000-0003-1263-5065
Jie XuPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-7842-5496
Xiaodan GuSchool of Polymer Science and Engineering, Center for Optoelectronic Materials and Devices, University of Southern Mississippi, Hattiesburg, MS 39406, USA.ORCID 0000-0002-1123-3673
Bozhi TianDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-0593-0023
Sihong WangPritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-3611-0004

Funding

Immunocompatible electronic polymers and devices for implantable sensors and stimulators that resist foreign-body responsesDP2EB034563 · NIBIB · UNIVERSITY OF CHICAGO · PI WANG, SIHONG · 2022 to 2025
$2.3M
NIBIB NIH HHS DP2 EB034563
6 · The paper itself

Abstract

Hydrogels, known for their mechanical and chemical similarity to biological tissues, are widely used in biotechnologies, whereas semiconductors provide advanced electronic and optoelectronic functionalities such as signal amplification, sensing, and photomodulation. Combining semiconducting properties with hydrogel designs can enhance biointeractive functions and intimacy at biointerfaces, but this is challenging owing to the low hydrophilicity of polymer semiconductors. We developed a solvent affinity-induced assembly method that incorporates water-insoluble polymer semiconductors into double-network hydrogels. These semiconductors exhibited tissue-level moduli as soft as 81 kilopascals, stretchability of 150% strain, and charge-carrier mobility up to 1.4 square centimeters per volt per second. When they are interfaced with biological tissues, their tissue-level modulus enables alleviated immune reactions. The hydrogel's high porosity enhances molecular interactions at semiconductor-biofluid interfaces, resulting in photomodulation with higher response and volumetric biosensing with higher sensitivity.

Identifiers

PMID39446940
PMCPMC12392907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.