Evidence map›Paper›PMID 39446807›Full record

ArticlePloS one2024

Ischemic mitral regurgitation: To repair or replace? A single center experience.

Joseph C Sweeney, Amal Alotaibi, Gene D Porter, Divya Avula, Jaimin R Trivedi, Mark S Slaughter, Brian L Ganzel, Siddharth V Pahwa

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joseph C SweeneyDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, Kentucky, United States of America.ORCID 0000-0003-2516-5875
Amal AlotaibiSchool of Medicine, University of Louisville, Louisville, Kentucky, United States of America.
Gene D PorterDepartment of Surgery, University of Kentucky, Lexington, Kentucky, United States of America.
Divya AvulaDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, Kentucky, United States of America.
Jaimin R TrivediDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, Kentucky, United States of America.ORCID 0000-0001-7152-1338
Mark S SlaughterDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, Kentucky, United States of America.ORCID 0000-0001-5412-762X
Brian L GanzelDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, Kentucky, United States of America.
Siddharth V PahwaDepartment of Cardiothoracic Surgery, University of Louisville, Louisville, Kentucky, United States of America.ORCID 0000-0001-9190-984X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecent reports on ischemic mitral valve (MV) regurgitation surgical strategies have suggested better hemodynamic performance with MV replacement (MVR) than MV repair (MVr) with no survival difference at 2 years. We evaluated the difference between MVR and MVr outcomes in patients with ischemic MR, including hemodynamic MV performance at 1 and 2 years postoperatively.

methodsA single center cardiac surgery database was queried for patients (aged >/ = 18 years) requiring mitral valve surgery with concomitant CABG or PCI between January 2010 and June 2018. Patients were separated into two groups: mitral valve repair using ring annuloplasty (MVr) and mitral valve replacement (MVR).

resultsA total of 111 patients (median age 66 years, 76% male) underwent an operation for ischemic mitral regurgitation during the study period. (44%) had MVr and 62 (56%) had MVR. Both groups had > 80% concomitant CABG. The MVr group had lower EF (40% vs. 55%, p < 0.01), shorter cardiopulmonary bypass time (117 vs. 164 minutes, p < .01) and shorter aortic cross-clamp time (80 vs. 116 minutes, p < .01). The in-hospital mortality (6% vs. 10%, p = 1.00) and 1-year mortality (14% vs. 18%, p = 0.17) were similar between the groups. Pre-operative left ventricular internal diameter at end-diastole was greater in the MVr group (5.6cm vs. 4.6cm, p < .01). At 1-year, more patients in the MVR group had no or trace regurgitation (29% vs. 61%, p = 0.01), however, the number of patients with moderate or greater mitral regurgitation was similar (6% vs. 12%, p = 0.69). At 2-years, the MVr and MVR groups had no difference in moderate or severe mitral regurgitation (7% vs. 13%, p = 0.68).

conclusionOur findings demonstrate similar early mortality and mid-term mitral valve performance, suggesting that MV repair could be a good surgical option in patients with ischemic MR requiring surgical revascularization.

Indexed as

Mitral ValveMitral Valve InsufficiencyMyocardial IschemiaAgedCoronary Artery BypassFemaleHeart Valve Prosthesis ImplantationHemodynamicsHospital MortalityHumansMaleMiddle AgedMitral Valve AnnuloplastyRetrospective StudiesTreatment Outcome

Identifiers

PMID39446807
PMCPMC11500968

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.