Evidence map›Paper›PMID 39446780›Full record

Observational studyPloS one2024

Vascular access devices and associated complications in paediatric critical care: A prospective cohort study.

Melany Gaetani, Sarah Kleiboer, Randolph Kissoon, Kristen Middaugh, Christopher S Parshuram

Abstract readObservational Study
In one paragraph

Observational study in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Core Tenets of Central Venous Access in Children.Seminars in interventional radiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melany GaetaniChild Health Evaluative Sciences, The Research Institute Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-3168-9029
Sarah KleiboerCenter for Safety Research, Toronto, Ontario, Canada.
Randolph KissoonCenter for Safety Research, Toronto, Ontario, Canada.
Kristen MiddaughChild Health Evaluative Sciences, The Research Institute Hospital for Sick Children, Toronto, Ontario, Canada.
Christopher S ParshuramChild Health Evaluative Sciences, The Research Institute Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-7744-481X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThough 60-80% of hospitalized patients have an intravascular device placed during hospitalization, there is a substantial risk of complication related to the placement, maintenance and removal of these devices. The objectives of this study were to describe vascular access device use, device complications and lumen dysfunction.

methodsAn observational cohort study was conducted over a 4.5 years period, in two quaternary, university-affiliated paediatric intensive care units (ICU). Eligible patients were admitted to either the paediatric or cardiac ICU and had one or more vascular access devices in-situ at the time of enrolment. Vascular access devices were defined as any external connection directly into the circulation including peripheral and central veins, arteries or bone marrow. Consistent with practice in the studied ICUs removal of peripheral catheters was regarded as due to dysfunction or complication.

results220 patients, 683 devices and 924 lumens were observed. The device complication rate was 21% and the lumen complication rate was 25%. The median duration without complication was 18 days for arterial catheters, 14 days for central venous catheters; 13 days for peripherally inserted central catheters and 4 days for peripheral intravenous catheters. On one third of all patient days, the volume of fluid administered to maintain VADs was equal to or greater than 20% of the total hourly total fluid intake.

conclusionApproximately 1 in 5 vascular devices had one or more complications in ICU, most devices continued to be used without removal, and some complications resolved. The implications of the fluids infused to maintain device function warrants further study, as do strategies to resolve or limit the their complications in children.

Indexed as

Critical CareIntensive Care Units, PediatricVascular Access DevicesAdolescentCatheterization, Central VenousCentral Venous CathetersChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleProspective Studies

Identifiers

PMID39446780
PMCPMC11500871

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.