Evidence map›Paper›PMID 39446767›Full record

Trial reportPloS one2024

Mind your pain: A single-arm feasibility study to assess a smartphone-based interoceptive attention training for patients with chronic low back pain.

Wolf E Mehling, Irina A Strigo, Veronica Goldman, Wendy Hartogensis, Shelley R Adler, Jeffrey Lotz, Frederick M Hecht

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06186193 (Mind Your Pain), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06186193 completednot on this map

Mind Your Pain: Validating the Mindful Interoceptive Exposure Task (MIET) for Patients With Chronic Low Back Pain

TypeobservationalSponsorUniversity of California, San FranciscoRan2021 to 2023Enrolled31ConditionsChronic Low-back PainArmsMyP
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. The Intersection of Interoception and Anticipation Related to Pain.Current topics in behavioral neurosciences · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wolf E MehlingOsher Center for Integrative Health & Department of Family and Community Medicine, University of California, San Francisco, San Francisco, California, United States of America.ORCID 0000-0002-0932-9844
Irina A StrigoDepartment of Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California, United States of America.ORCID 0000-0002-8799-716X
Veronica GoldmanOsher Center for Integrative Health, University of California, San Francisco, San Francisco, California, United States of America.
Wendy HartogensisOsher Center for Integrative Health, University of California, San Francisco, San Francisco, California, United States of America.
Shelley R AdlerOsher Center for Integrative Health & Department of Family and Community Medicine, University of California, San Francisco, San Francisco, California, United States of America.ORCID 0000-0001-6637-9533
Jeffrey LotzDepartment of Orthopedic Surgery, University of California, San Francisco, San Francisco, California, United States of America.
Frederick M HechtOsher Center for Integrative Health & Department of Medicine, University of California, San Francisco, San Francisco, California, United States of America.

Funding

UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back PainU19AR076737 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LOTZ, JEFFREY C. · 2019 to 2023
$34.1M
Skeletal Biology and Biomechanics (SBB) CoreP30AR075055 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Wenhan Chang · 2019 to 2026
$7.1M
CSRD VA IK6 CX002926NIAMS NIH HHS P30 AR075055NIAMS NIH HHS U19 AR076737
6 · The paper itself

Abstract

objectivePeople commonly cope with chronic low back pain (cLBP) by ignoring and distraction. Can mindful interoceptive exposure to the pain sensation itself and its phenomenological components be an alternative approach?

methodsSingle-arm feasibility study in patients with cLBP using a 2-minute attention exercise guided by a smartphone app several times per day over 8 weeks. We assessed feasibility, pre/post pain, function, and psychological parameters using mixed methods: standard questionnaires, ecological momentary assessment, and exit interviews that included micro-phenomenology technique and subsequent reflexive thematic qualitative analysis.

resultsWe enrolled 31 participants, mostly female, mean age 48, the majority had pain for >5 years; 29 completed. Mean pain intensity [0-10] improved from 4.8 ±1.7 to 3.1 ±1.9 (p < .0001); mean PEG scores (intensity and interference with daily life; range 0-30) improved from 13.7 ±6.2 to 8.4 ±6.6 (p < .0001); pain impact (9 items incl physical function) 22.3 ±8.7 to 19.7 ±8.1 (p = .0010). Twenty-one of 29 improved PEG score ≥30%. There were significant improvements in PCS Rumination and MAIA Not-Worrying. Participants became aware of their usual habit of avoidance and the challenge of and resistance to focusing on pain. They were surprised how pain sensations varied over time, and that pain intensity and the threat value of pain could diminish by focusing on it. They described a variety of 3D pain shapes (e.g., football, pool ball, rod, nail, brick, stars) with a range of colors, transparency, temperature, and density that for some changed with mindful attention. Most struggled to find appropriate words for sensory awareness and attention regulation and found that the threat value of their pain diminished.

conclusionsMindful interoceptive exposure to the sensations of their cLBP using a 2-minute attention exercise with a phone app-rather than ignoring and distracting from it-may be a beneficial intervention for cLBP.

trial registrationClinicalTrials.gov #NCT06186193.

Indexed as

AttentionChronic PainFeasibility StudiesLow Back PainSmartphoneAdultFemaleHumansInteroceptionMaleMiddle AgedMindfulnessMobile ApplicationsPain Measurement

Identifiers

PMID39446767
PMCPMC11500934

What OpenQuestion holds

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LicenceCC0
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.