Evidence map›Paper›PMID 39446757›Full record

ArticleRejuvenation research2025

Moxibustion Regulates the Expression of T Cells in Rheumatoid Arthritis Through Tim-3/Gal-9 Signaling Pathway.

Yu-Mei Zhong, Kun Luo, Yan-Ding Guo, Xiu-Hua Gao, Hai-Yan Zhou

Abstract read
In one paragraph

Article in Rejuvenation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Mei ZhongChengdu First People's Hospital/Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Kun LuoAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yan-Ding GuoAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiu-Hua GaoHealth Rehabilitation School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hai-Yan ZhouAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To observe the effects of moxibustion on T cells and T cell immunoglobulin and mucin-domain-containing molecule-3/galectin-9 (Tim-3/Gal-9) pathway in rats with rheumatoid arthritis (RA). To further explore the possible anti-inflammatory mechanism of moxibustion in the treatment of RA. Thirty Sprague Dawley rats were randomly divided into three groups, including a control group, an RA model group, and a moxibustion group. An RA model was created through the injection of Freund's complete adjuvant. In the moxibustion group, rats were treated with moxibustion at acupoints of "Shenshu" and "Zusanli." A total of three courses of treatment were conducted. Then the thickness of foot pad was measured, joint pathological changes were observed by hematoxylin-eosin (HE) staining, the proportion of CD4

Indexed as

Arthritis, RheumatoidGalectinsHepatitis A Virus Cellular Receptor 2MoxibustionSignal TransductionT-LymphocytesAnimalsCD4-Positive T-LymphocytesMaleRatsRats, Sprague-DawleySynovial MembraneGalectinsHepatitis A Virus Cellular Receptor 2moxibustionRAT cellTim-3

Identifiers

PMID39446757
PMCPMC11844223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.