Evidence map›Paper›PMID 39446235›Full record

ArticleJournal of general internal medicine2025

Taxpayers' Share of US Prescription Drug and Insulin Costs: a Cross-Sectional Study.

Elizabeth Schrier, David U Himmelstein, Adam Gaffney, Danny McCormick, Steffie Woolhandler

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Estimating US savings on outpatient prescription pharmaceuticals from international reference pricing.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth SchrierInternal Medicine Residency Program, Department of Medicine, University of California, San Francisco, CA, USA. Elizabeth.schrier@ucsf.edu.ORCID 0000-0001-5118-6085
David U HimmelsteinCity University of New York at Hunter College, New York, NY, USA.
Adam GaffneyDepartment of Medicine, Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, USA.
Danny McCormickDepartment of Medicine, Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, USA.
Steffie WoolhandlerCity University of New York at Hunter College, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug prices affect government budgets directly through spending on public programs like Medicare and Medicaid, and indirectly via private coverage for public employees and tax subsidies for private insurance. Yet, the Senate parliamentarian ruled that the Senate could not use streamlined Budget Reconciliation to extend the Inflation Reduction Act's controls on insulin co-payment or drug prices to private insurers on the grounds that their expenditures do not affect the federal budget.

objectiveTo quantify insulin and other drug costs borne by federal, state, and local governments, including direct expenditures and indirect government subsidies that flow through private insurers.

designCross-sectional analysis of expenditures for outpatient retail prescription drugs reported by respondents and their pharmacies in the 2019 Medical Expenditure Panel Survey (adjusted downward for drug rebates), supplemented with information on employment-related insurance from the US Office of Management and Budget and other sources.

participantsThe civilian non-institutionalized US population. MAIN MEASURES: Direct (payments by public health insurance programs) and indirect (taxpayer-funded payments via private insurers) government expenditures for outpatient retail drugs. KEY

resultsDirect government expenditures for outpatient retail prescription drugs totaled $154.85 billion in 2019, including $15.68 billion for insulin. Indirect government expenditures channeled through private insurers totaled $53.59 billion (including $5.48 billion for insulins). Those indirect expenditures encompassed $32.32 billion in tax subsidies for employer-sponsored private coverage, $25 million for subsidies to private Affordable Care Act marketplace plans, and $21.24 billion for government-paid premiums for public employees and retirees. Overall, government expenditures for outpatient retail prescription drugs totaled $208.44 billion, 58.76% of all-payer spending and 65.96% of spending for insulin.

conclusionsGovernments directly or indirectly fund most drug purchases, including substantial expenditures that flow through private insurers. Hence, prices paid by private insurers impact government budgets, supporting the view that government should be allowed to regulate drug prices.

Indexed as

Drug CostsHealth ExpendituresInsulinPrescription DrugsTaxesCross-Sectional StudiesFemaleHumansMaleUnited StatesInsulinPrescription Drugscosts and spendingdiabetesinsurance coverage and benefitsMedicaidMedicareprescription drugsprivate health insurance

Identifiers

PMID39446235
PMCPMC12045909

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.