Evidence map›Paper›PMID 39446198›Full record

ArticleHuman cell2024

Generation of CRISPR/Cas9 modified human iPSC line with correction of heterozygous mutation in exon 6 of the CaSR gene.

P I Semenova, A V Panova, J V Sopova, O A Krasnova, V I Turilova, T K Yakovleva, K S Kulikova, D A Petrova, S L Kiselev, I E Neganova

Abstract read
PubMed Publisher
In one paragraph

Article in Human cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

P I Semenova *The Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, 194064, Russia.ORCID http://orcid.org/0009-0002-5891-6460
A V Panova *Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.ORCID http://orcid.org/0000-0002-1102-2374
J V SopovaThe Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, 194064, Russia.ORCID http://orcid.org/0000-0002-7825-273X
O A KrasnovaThe Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, 194064, Russia.
V I TurilovaThe Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, 194064, Russia.
T K YakovlevaThe Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, 194064, Russia.
K S KulikovaResearch Centre for Medical Genetics, Moscow, 115478, Russia.ORCID http://orcid.org/0000-0002-0434-9088
D A PetrovaEndocrinology Research Centre, Moscow, 115478, Russia.
S L KiselevVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 117971, Russia.
I E NeganovaThe Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, 194064, Russia. irina.neganova@incras.ru.ORCID http://orcid.org/0000-0001-5712-2170

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2021-1075
6 · The paper itself

Abstract

The calcium-sensing receptor (CaSR) gene encodes a cell membrane G protein-coupled receptor (GPCR) which has a key role in maintaining the extracellular Ca

Indexed as

CRISPR-Cas SystemsExonsHeterozygoteInduced Pluripotent Stem CellsMutationReceptors, Calcium-SensingCell DifferentiationCell LineGene EditingHumansHyperparathyroidism, PrimaryInfant, NewbornInfant, Newborn, DiseasesPrecision MedicineCASR protein, humanReceptors, Calcium-SensingCalcium-sensing receptorGenome editingInduced mesenchymal stem cellsInduced pluripotent stem cells

Identifiers

PMID39446198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.