Evidence map›Paper›PMID 39446148›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Beneficial effects of resveratrol on diabetes mellitus and its complications: focus on mechanisms of action.

Amir Mahmoud Ahmadzadeh, Mehraneh Movahedi Aliabadi, Seyed Behzad Mirheidari, Mahdie Hamedi-Asil, Setareh Garousi, Mehran Mottahedi, Amirhossein Sahebkar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amir Mahmoud AhmadzadehDepartment of Radiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehraneh Movahedi AliabadiAllergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed Behzad MirheidariDepartment of Medicine, Golestan University of Medical Sciences, Golestan, Iran.
Mahdie Hamedi-AsilSchool of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Setareh GarousiDepartment of Surgical and Interventional Sciences, McGill University, Montreal, Quebec, Canada.
Mehran MottahediDepartment of Surgical and Interventional Sciences, McGill University, Montreal, Quebec, Canada.
Amirhossein SahebkarCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India. amir_Saheb2000@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) is a significant global health issue, associated with various microvascular and macrovascular complications that significantly impair patients' quality of life as well as healthspan and lifespan. Despite the availability of several anti-diabetic medications with different mechanisms of action, there remains no definite curative treatment. Hence, discovering new efficient complementary therapies is essential. Natural products have received significant attention due to their advantages in various pathological conditions. Resveratrol is a natural polyphenol that possesses antioxidant and anti-inflammatory properties, and its efficacy has been previously investigated in several diseases, including DM. Herein, we aimed to provide a holistic view of the signaling pathways and mechanisms of action through which resveratrol exerts its effects against DM and its complications.

Indexed as

AntioxidantsDiabetes ComplicationsDiabetes MellitusHypoglycemic AgentsResveratrolAnimalsAnti-Inflammatory AgentsHumansSignal TransductionAnti-Inflammatory AgentsAntioxidantsHypoglycemic AgentsResveratrolDiabetes mellitusHerbal medicinePhytochemicalPhytotherapyResveratrol

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.