ArticlemSystems2024
Pooled analysis of oral microbiome profiles defines robust signatures associated with periodontitis.
Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed.
- Longitudinal gut microbiome dynamics are associated with clinical outcome and toxicity during ibrutinib therapy.Gut microbes · 2026Article
- Exploring the oral microbiome diversity and genus signatures associated with a novel non-invasive metabolic indicator: a cross-sectional study.The Saudi dental journal · 2026Article
- Metagenomic profiling and predictive modeling of the gut microbiome reveal signatures of gestational disease.Microbiology spectrum · 2026Article
- Potential biomarkers for early periodontal inflammation: investigating CD5Scientific reports · 2026Article
- Microbial Diversity and Composition Uncovered on Obturator Prosthesis Biofilms: Exploratory Findings from a Pilot Study.Pathogens (Basel, Switzerland) · 2026Article
- Oral microbiome profiles by periodontitis stage in a Korean population.Frontiers in cellular and infection microbiology · 2026Article
- Oral microbiome contribution in colorectal carcinogenesis: polymicrobial interactions and virulence determinants.Frontiers in cellular and infection microbiology · 2026Review
- Traditional medicine and natural product based therapeutics in gingivitis management and microbial interactions.Frontiers in antibiotics · 2026Review
- Antibacterial Agent-Loaded, Novel In Situ Forming Implants Made with Poly(Isosorbide Sebacate) and Dimethyl Isosorbide as a Solvent for Periodontitis Treatment.Molecules (Basel, Switzerland) · 2025Article
- Exploring the Oral Microbiome: Understanding its Impact on the Development of Oral Squamous Cell Carcinoma.Current microbiology · 2025Review
- Full-length 16S rRNA sequencing reveals microbial characteristics in supragingival plaque of periodontitis patients.Journal of dental sciences · 2025Article
- Comparison of red complex bacteria and antimicrobial resistance genes in stage III/IV periodontitis patients with and without type 2 diabetes mellitus: A cross-sectional observational study.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Oral microbial dysbiosis has been associated with periodontitis in studies using 16S rRNA gene sequencing analysis. However, this technology is not sufficient to consistently separate the bacterial species to species level, and reproducible oral microbiome signatures are scarce. Obtaining these signatures would significantly enhance our understanding of the underlying pathophysiological processes of this condition and foster the development of improved therapeutic strategies, potentially personalized to individual patients. Here, we sequenced newly collected samples from 24 patients with periodontitis, and we collected available oral microbiome data from 24 samples in patients with periodontitis and from 214 samples in healthy individuals ( IMPORTANCE: Oral microbial dysbiosis has been associated with periodontitis in studies using 16S rRNA gene sequencing analysis. However, this technology is not sufficient to consistently separate the bacterial species to species level, and reproducible oral microbiome signatures are scarce. Here, using ultra-deep metagenomic sequencing and machine learning tools, we defined a simple two-factor decision tree, based on
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