Evidence map›Paper›PMID 39445520›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Microfabrication Technologies for Nanoinvasive and High-Resolution Magnetic Neuromodulation.

Changhao Ge, Tahereh Masalehdan, Mahdieh Shojaei Baghini, Vicente Duran Toro, Lorenzo Signorelli, Hannah Thomson, Danijela Gregurec, Hadi Heidari

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. "Tone-Arm" Neuromodulation MEMS Microcoil for In Vivo Imaging.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Genetics-Based Targeting Strategies for Precise Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Microfabrication Technologies for Nanoinvasive and High-Resolution Magnetic Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Changhao GeMicroelectronics Lab (meLAB), James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.
Tahereh MasalehdanMicroelectronics Lab (meLAB), James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.
Mahdieh Shojaei BaghiniMicroelectronics Lab (meLAB), James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.
Vicente Duran ToroBiointerfaces lab, Faculty of Sciences, Friedrich-Alexander-Universität Erlangen-Nürnberg, Henkestraße 91, 91052, Erlangen, Germany.
Lorenzo SignorelliBiointerfaces lab, Faculty of Sciences, Friedrich-Alexander-Universität Erlangen-Nürnberg, Henkestraße 91, 91052, Erlangen, Germany.
Hannah ThomsonMicroelectronics Lab (meLAB), James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.
Danijela GregurecBiointerfaces lab, Faculty of Sciences, Friedrich-Alexander-Universität Erlangen-Nürnberg, Henkestraße 91, 91052, Erlangen, Germany.
Hadi HeidariMicroelectronics Lab (meLAB), James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.ORCID 0000-0001-8412-8164

Funding

BRAINSTORM 101099355HORIZON EUROPE Framework Programme 101070908Innovate UK 10053123
6 · The paper itself

Abstract

The increasing demand for precise neuromodulation necessitates advancements in techniques to achieve higher spatial resolution. Magnetic stimulation, offering low signal attenuation and minimal tissue damage, plays a significant role in neuromodulation. Conventional transcranial magnetic stimulation (TMS), though noninvasive, lacks the spatial resolution and neuron selectivity required for spatially precise neuromodulation. To address these limitations, the next generation of magnetic neurostimulation technologies aims to achieve submillimeter-resolution and selective neuromodulation with high temporal resolution. Invasive and nanoinvasive magnetic neurostimulation are two next-generation approaches: invasive methods use implantable microcoils, while nanoinvasive methods use magnetic nanoparticles (MNPs) to achieve high spatial and temporal resolution of magnetic neuromodulation. This review will introduce the working principles, technical details, coil designs, and potential future developments of these approaches from an engineering perspective. Furthermore, the review will discuss state-of-the-art microfabrication in depth due to its irreplaceable role in realizing next-generation magnetic neuromodulation. In addition to reviewing magnetic neuromodulation, this review will cover through-silicon vias (TSV), surface micromachining, photolithography, direct writing, and other fabrication technologies, supported by case studies, providing a framework for the integration of magnetic neuromodulation and microelectronics technologies.

Indexed as

MicrotechnologyTranscranial Magnetic StimulationHumansmagnetic stimulationmicrofabricationnanoinvasiveneuromodulationneurophysiology

Identifiers

PMID39445520
PMCPMC11633526

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.