ArticleCureus2024
FBXW7 as a Factor of the African American and White Breast Cancer Racial Disparity.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
introductionAfrican American women have a breast cancer mortality rate 40% higher than Caucasian women. Many contributing factors account for this racial disparity, such as socioeconomic status and the age when women give birth, but even after considering such factors, studies have found that the racial disparity persists, suggesting that genetic factors may play a crucial role in this breast cancer racial inequality.
methodsThis study utilizes the All of Us database, The Cancer Genome Atlas (TCGA), and an array of bioinformatics tools to integrate differential mutation and gene expression analyses, aiming to identify genes potentially associated with this racial disparity. Although previous studies have identified genes associated with this breast cancer racial disparity through mutation or gene expression analysis, no studies have considered both simultaneously. Ultimately, this study considers both mutation and gene expression to discover novel genes linked to this racial disparity.
resultsAfter mutation analysis, this study identified
conclusionBy combining both mutation and gene expression analysis, this research offers a unique perspective into this issue. Furthermore, the identification of
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