Evidence map›Paper›PMID 39445273›Full record

ArticleCureus2024

Cytotoxic Lesions of the Corpus Callosum (CLOCCs) Related to Hypoglycemia: Clinical Insights and Pathogenesis.

Koji Hayashi, Yuka Nakaya, Midori Ueda, Maho Hayashi, Shin-Ichiro Azuma, Asuka Suzuki, Mamiko Sato, Yasutaka Kobayashi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Koji HayashiDepartment of Rehabilitation Medicine, Fukui General Hospital, Fukui, JPN.
Yuka NakayaDepartment of Rehabilitation Medicine, Fukui General Hospital, Fukui, JPN.
Midori UedaDepartment of Rehabilitation Medicine, Fukui General Hospital, Fukui, JPN.
Maho HayashiDepartment of Internal Medicine, Fukui General Hospital, Fukui, JPN.
Shin-Ichiro AzumaDepartment of Internal Medicine, Fukui General Hospital, Fukui, JPN.
Asuka SuzukiDepartment of Rehabilitation Medicine, Fukui General Hospital, Fukui, JPN.
Mamiko SatoDepartment of Rehabilitation Medicine, Fukui General Hospital, Fukui, JPN.
Yasutaka KobayashiGraduate School of Health Science, Fukui Health Science University, Fukui, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the case of an 88-year-old man with cytotoxic lesions of the corpus callosum (CLOCCs) related to hypoglycemia. The patient developed a disturbance of consciousness following excessive alcohol consumption and anorexia. In the emergency room, his blood sugar level was 9 mg/dL, and he was immediately treated with a rapid infusion of glucose. Brain magnetic resonance imaging (MRI) revealed hyperintensity in the corpus callosum and bilateral deep white matter on diffusion-weighted imaging, along with decreased apparent diffusion coefficient values. The following day, these findings were attenuated, and he was diagnosed with CLOCCs. In this report, we discuss clinical insights and the possible pathogenesis of the development of CLOCCs due to hypoglycemia, considering the previous literature.

Indexed as

cytotoxic lesions of the corpus callosumhypoglycemiamild encephalitis/encephalopathy with a reversible isolated splenial lesionreversible splenial lesions and reversible splenial lesion syndromesplenium of the corpus callosum

Identifiers

PMID39445273
PMCPMC11497060

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.