Evidence map›Paper›PMID 39445270›Full record

ArticleCureus2024

HIV-Associated Thrombotic Thrombocytopenic Purpura in a Virally Suppressed Patient With Normal CD4 Count: A Rare Presentation.

Ammad Naeem, Ahsan Khan, Khawaja O Omar, Amir Kamran

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ammad NaeemHospital Medicine, Charleston Area Medical Center, Charleston, USA.
Ahsan KhanInternal Medicine, West Virginia School of Osteopathic Medicine, Lewisburg, USA.
Khawaja O OmarPulmonary and Critical Care Medicine, Charleston Area Medical Center, Charleston, USA.
Amir KamranHematology and Oncology, Charleston Area Medical Center, Charleston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic process characterized by multiorgan failure secondary to microvascular thrombi comprising platelets and von Willebrand factor. HIV is a known risk factor for TTP. However, patients generally have low CD4+ count during initial presentation or subsequent flare-ups. This case report describes a 69-year-old man with HIV who presented with an initial presentation of TTP while having a prior history of HIV with a normal CD4 count and undetectable viral load on presentation. A 69-year-old Caucasian male with a previous history of HIV on antiretroviral therapy (ART), a history of recurrent deep vein thrombosis maintained on Coumadin, and no previous history of tobacco dependence or substance use presented to the emergency department with symptoms of fatigue and dyspnea worsening on exertion. The patient had stable vital signs on arrival. The initial lab workup was remarkable for hemoglobin of 9.3 g/dL, hematocrit 29%, platelets 22 x 10

Indexed as

anemiaaquired ttpautoimmune haemolytic anemiacd4+ counthaart therapyimmune hematologypeople living with hiv/aidsrefractory ttpthrombocytopeniathrombotic thrombocytopenic thrombocytopenia

Identifiers

PMID39445270
PMCPMC11497860

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.