Evidence map›Paper›PMID 39445053›Full record

ArticleCase reports in neurological medicine2024

New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination.

Chun Seng Phua, Azman Ali Raymond, Shalini Bhaskar

Abstract readCase Reports
In one paragraph

Article in Case reports in neurological medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chun Seng PhuaMonash University, Department of Neurosciences, Wellington Road, Clayton 3800, Victoria, Australia.ORCID https://orcid.org/0000-0001-9129-3918
Azman Ali RaymondFaculty of Medicine, Universiti Teknologi MARA, JLN Hospital, Sungai Buloh 47000, Selangor, Malaysia.ORCID https://orcid.org/0000-0001-6066-5168
Shalini BhaskarFaculty of Medicine, Universiti Teknologi MARA, JLN Hospital, Sungai Buloh 47000, Selangor, Malaysia.ORCID https://orcid.org/0000-0002-9169-4209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 18-year-old male presented with new-onset focal to bilateral tonic-clonic seizures 5 days after receiving the first dose of COVID-19 vaccine. 3 days later, an identical seizure occurred lasting 1 min, leading to an acute presentation to the hospital. In hospital, the patient was loaded with intravenous phenytoin and started on levetiracetam with no further seizure recurrence. CT venogram and scalp EEG were unremarkable. MRI brain revealed generalised atrophy with mild bilateral hippocampal atrophy. The patient was maintained on 500 mg levetiracetam twice daily and advised to proceed with subsequent doses of vaccination. Vaccinations have been associated with breakthrough seizures. In this case, COVID-19 vaccination possibly unmasked an underlying predisposition for epilepsy.

Indexed as

COVID-19epilepsyfocal seizureseizure thresholdvaccination

Identifiers

PMID39445053
PMCPMC11498974

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.