Evidence map›Paper›PMID 39444941›Full record

ArticleRSC advances2024

Mechanistic insights into carbonic anhydrase IX inhibition by coumarins from

Reem S Alruhaimi, Emadeldin M Kamel, Sulaiman M Alnasser, Mohammed A Alzoghaibi, Al Mokhtar Lamsabhi, Ayman M Mahmoud

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Chronic Administration ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Reem S AlruhaimiDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University Riyadh 11671 Saudi Arabia.
Emadeldin M KamelOrganic Chemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62514 Egypt.ORCID https://orcid.org/0000-0002-1279-9564
Sulaiman M AlnasserDepartment of Pharmacology and Toxicology, College of Pharmacy, Qassim University Qassim 51452 Saudi Arabia.
Mohammed A AlzoghaibiPhysiology Department, College of Medicine, King Saud University Riyadh 11461 Saudi Arabia.
Al Mokhtar LamsabhiDepartamento de Química, Universidad Autónoma de Madrid, Campus de Excelencia UAM-CSIC Cantoblanco Módulo 13 Madrid 28049 Spain.ORCID https://orcid.org/0000-0002-1509-2513
Ayman M MahmoudDepartment of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University Manchester M1 5GD UK a.mahmoud@mmu.ac.uk.ORCID https://orcid.org/0000-0003-0279-6500

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the critical role of carbonic anhydrase IX (CA IX) in various pathological conditions, there is a significant demand for new inhibitors to enhance patient outcomes and clinical management. In this study, we examined the inhibitory effectiveness of five coumarins derived from

Identifiers

PMID39444941
PMCPMC11497074

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.