ArticleJournal of thoracic disease2024
Preoperative localization of pulmonary nodules by electromagnetic navigation bronchoscopy combined with methylene blue injection.
Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Clinical evaluation of the effectiveness of laser localization system in CT-guided percutaneous lung puncture positioning: a prospective randomized controlled pilot study.Quantitative imaging in medicine and surgery · 2026Article
- Preoperative and intraoperative localization of small pulmonary nodules for thoracoscopic surgery: a contemporary narrative review.Journal of robotic surgery · 2026Review
- Comparison of Two Dye Marking Methods for Preoperative Localization of Pulmonary Nodules Guided by Electromagnetic Navigation Bronchoscopy.Thoracic cancer · 2026Article
- Robotic-assisted optical navigation system for CT-guided preoperative percutaneous Hook-wire localization of pulmonary nodules: a prospective, single-center, single-arm clinical study.World journal of surgical oncology · 2026Article
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6 authors.
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Abstract
Background: Electromagnetic navigation bronchoscopy (ENB) can help to accurately locate pulmonary nodules using a minimally invasive approach. This study sought to evaluate the clinical efficacy and safety of dye marking localization under the guidance of ENB followed by surgery. Methods: A retrospective analysis was performed of 61 patients who underwent ENB localization using methylene blue dye marking before surgery at Shanghai General Hospital from October 2021 to February 2022. The clinical efficacy and safety of ENB localization and the related factors affecting the navigation time of ENB location were analyzed. Results: ENB was performed on 170 pulmonary nodules in 61 patients with a median age of 60 [interquartile range (IQR), 18] years. The majority of patients (70.69%) had more than two pulmonary nodules. The median maximum nodule diameter was 10 (IQR, 8) mm, and 48.21% of the nodules were mixed ground-glass nodules. Median time for ENB navigation was 10.5 (IQR, 6) min. The navigation success rate was 92.96%, and the ENB location success rate was 95.89%. The rate of complications related to ENB localization was 1.64% (there was only one case of pulmonary hemorrhage). The multivariate analysis showed that the factors related to the navigation time included the node location (P=0.001) and location mode (P=0.04). Conclusions: ENB-guided methylene blue injection is an effective and safe tool for localizing and marking pulmonary nodules, and can be used to assist the diagnosis and treatment of early lung cancer. The node location and location mode had significant effects on navigation time.
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