Evidence map›Paper›PMID 39444844›Full record

ArticleJournal of polymer science (2020)2024

Engineering of bioorthogonal polyzymes through polymer sidechain design.

Cristina-Maria Hirschbiegel, Ritabrita Goswami, Soham Chakraborty, Cedar Noonan, Edward Pham, Harini Nagaraj, William Ndugire, Stefano Fedeli, Vincent M Rotello

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of polymer science (2020), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Polymer-siRNA nanovectors for treating lung inflammation.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cristina-Maria HirschbiegelUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
Ritabrita GoswamiUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
Soham ChakrabortyUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
Cedar NoonanUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
Edward PhamUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
Harini NagarajUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
William NdugireUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
Stefano FedeliUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.
Vincent M RotelloUniversity of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01035, USA.

Funding

Chemistry-Biology Interface Predoctoral Training GrantT32GM139789 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ERIC Robert STRIETER · 2021 to 2026
$3.4M
Targeting of Bio-orthogonal Chemotherapeutic Nanozymes to Tumor-Associated MacrophagesR01EB022641 · NIBIB · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ROTELLO, VINCENT M. · 2017 to 2024
$3.0M
NIBIB NIH HHS R01 EB022641NIGMS NIH HHS T32 GM139789
6 · The paper itself

Abstract

Synthetic polymer scaffolds can encapsulate transition metal catalysts (TMCs) to provide bioorthogonal nanocatalysts. These 'polyzymes' catalyze the

Indexed as

bioorthogonal catalysisnanocatalystspolyzymes

Identifiers

PMID39444844
PMCPMC11495851

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.