ArticleJAAD international2024
Chronic disease associated with bullous pemphigoid risk: A systematic review and meta-analysis.
Article in JAAD international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Thematic Evolution and Diversification of Bullous Pemphigoid Research: A Bibliometric Analysis, 1959-2025.Clinical, cosmetic and investigational dermatology · 2026Article
- Localized genital blisters in an elderly male.JAAD case reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bullous pemphigoid (BP) is a chronic autoimmune blistering disease prevalent in the elderly, often accompanied by renal comorbidities. Immune dysregulation can lead to secondary BP and increased mortality rates in those already diagnosed. Methods: A literature review identified studies on the association between kidney disease and other comorbidities with BP. Pooled effect estimates were analyzed utilizing a random-effects model. Objective: To assess comorbidity risks with BP and determine mortality risk among BP patients with comorbidities. Results: Analysis included 45,323 BP patients from 49 studies. Kidney diseases were significantly linked to higher BP incidence (subdistribution hazard ratio 1.51, 95% CI: 1.10-2.07) and increased mortality (hazard ratio 1.62, 95% CI: 1.13-2.32). Cerebrovascular diseases, dementia, and diabetes also showed significant associations with both increased BP incidence and mortality ( Limitation: The study comprises mostly case-control, prospective, and retrospective observational studies, alongside data heterogeneity. Conclusion: This study reveals the association of several chronic conditions, including kidney diseases, with BP, contributing to elevated mortality rates. The findings emphasize the importance of management targeting both BP and associated comorbidities to improve patient outcomes.
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Registered trials
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