Evidence map›Paper›PMID 39444390›Full record

ReviewJournal of cardiovascular echography

Clinical Applications of Myocardial Work in Echocardiography: A Comprehensive Review.

Giancarlo Trimarchi, Scipione Carerj, Gianluca Di Bella, Roberta Manganaro, Fausto Pizzino, Davide Restelli, Giuseppe Pelaggi, Francesca Lofrumento, Roberto Licordari, Giovanni Taverna and 5 more

Abstract readReview
In one paragraph

Review in Journal of cardiovascular echography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  20. Arrhythmogenic Right Ventricular Cardiomyopathy: A Comprehensive Review.Journal of cardiovascular development and disease · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Giancarlo TrimarchiDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Scipione CarerjDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Gianluca Di BellaDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Roberta ManganaroDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Fausto PizzinoHeart Centre, Cardiology Unit, Fondazione Gabriele Monasterio, Massa, Italy.
Davide RestelliDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Giuseppe PelaggiDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Francesca LofrumentoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Roberto LicordariDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Giovanni TavernaDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Umberto ParadossiHeart Centre, Cardiology Unit, Fondazione Gabriele Monasterio, Massa, Italy.
Cesare de GregorioDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Antonio MicariDepartment of Biomedical and Dental Sciences and of Morphological and Functional Images, University of Messina, Messina, Italy.
Giovanna Di GiannuarioDepartment of Cardiology, Infermi Hospital, Rimini, Italy.
Concetta ZitoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular (LV) global longitudinal strain (GLS) has recently garnered attention as a reliable and objective method for evaluating LV systolic function. One of the key advantages of GLS is its ability to detect subtle abnormalities even when the ejection fraction (EF) appears to be preserved. However, it is important to note that GLS, much like LVEF, is significantly influenced by load conditions. In recent years, researchers and clinicians have been exploring noninvasive myocardial work (MW) quantification as an innovative tool for assessing myocardial function. This method integrates measurements of strain and LV pressure, providing a comprehensive evaluation of the heart's performance. Notably, MW offers an advantage over GLS and LVEF because it provides a load-independent assessment of myocardial performance. The implementation of commercial echocardiographic software that facilitates the noninvasive calculation of MW has significantly broadened the scope of its application. This advanced technology is now being utilized in multiple clinical settings, including ischemic heart disease, valvular diseases, cardiomyopathies, cardio-oncology, and hypertension. One of the fundamental aspects of MW is its correlation with myocardial oxygen consumption, which allows for the assessment of work efficiency. Understanding this relationship is crucial for diagnosing and managing various cardiac conditions. The aim of this review is to provide an overview of the noninvasive assessment of myocardial by echocardiography, from basic principles and methodology to current clinical applications.

Indexed as

Cardiomyopathiesechocardiographyglobal longitudinal strainheart failuremyocardial workspeckle-tracking echocardiographyvalvular diseases

Identifiers

PMID39444390
PMCPMC11495308

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.