Evidence map›Paper›PMID 39444222›Full record

ArticleBiofabrication2024

Dynamic culture of cerebral organoids using a pillar/perfusion plate for the assessment of developmental neurotoxicity.

Prabha Acharya, Sunil Shrestha, Pranav Joshi, Na Young Choi, Vinod Kumar Reddy Lekkala, Soo-Yeon Kang, Gabriel Ni, Moo-Yeal Lee

Abstract read
In one paragraph

Article in Biofabrication, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Prabha AcharyaDepartment of Biomedical Engineering, University of North Texas, Denton, TX, United States of America.
Sunil ShresthaDepartment of Biomedical Engineering, University of North Texas, Denton, TX, United States of America.
Pranav JoshiBioprinting Laboratories Inc., Dallas, TX, United States of America.
Na Young ChoiDepartment of Biomedical Engineering, University of North Texas, Denton, TX, United States of America.
Vinod Kumar Reddy LekkalaDepartment of Biomedical Engineering, University of North Texas, Denton, TX, United States of America.
Soo-Yeon KangDepartment of Biomedical Engineering, University of North Texas, Denton, TX, United States of America.
Gabriel NiDepartment of Biomedical Engineering, University of North Texas, Denton, TX, United States of America.
Moo-Yeal LeeDepartment of Biomedical Engineering, University of North Texas, Denton, TX, United States of America.ORCID 0000-0001-6922-609X

Funding

Modeling diabetes using an integrated plate systemUH3DK119982 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI LEE, MOO-YEAL, WELLS, JAMES M · 2020 to 2022
$5.4M
Pillar and perfusion well plate platforms for reproducible organoid culture from iPSCR44TR003491 · NCATS · BIOPRINTING LABORATORIES, INC. · PI JOSHI, PRANAV, LEE, MOO-YEAL · 2020 to 2021
$838k
Gene-edited liver organoids for predictive hepatotoxicityR43ES035653 · NIEHS · BIOPRINTING LABORATORIES, INC. · PI JOSHI, PRANAV, LEE, MOO-YEAL · 2023 to 2023
$285k
NCATS NIH HHS R44 TR003491NIDDK NIH HHS UH3 DK119982NIEHS NIH HHS R43 ES035653
6 · The paper itself

Abstract

Despite the potential toxicity of commercial chemicals to the development of the nervous system (known as developmental neurotoxicity or DNT), conventional

Indexed as

Methylmercury CompoundsOrganoidsBrainCell Culture TechniquesCell DifferentiationHumansNeurotoxicity SyndromesPerfusionMethylmercury Compoundscerebral organoidsdevelopmental neurotoxicitydynamic organoid cultureperfusion platepillar plate

Identifiers

PMID39444222
PMCPMC11542746

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.