ArticleInfectious diseases of poverty2024
Global burden of soil-transmitted helminth infections, 1990-2021.
Article in Infectious diseases of poverty, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 6 of them syntheses that pooled it.
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Who cites it
63 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Beyond Coverage: A Systematic Review and Thematic Analysis of Delivery, Compliance, Equity and Impact in Mass Deworming for Soil-Transmitted Helminths.Acta parasitologica · 2026Pooled it
- The Hidden Link Between Intestinal Helminthiasis, Gut Microbiome Alterations, and Colorectal Cancer Risk: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Global prevalence and public health impact of intestinal parasitic infections in children under five: a systematic review and meta-analysis.BMC public health · 2026Pooled it
- Comparison of Ritchie and Kato-Katz methods for the detection of intestinal helminths in humans: a systematic review and meta-analysis.Parasites & vectors · 2026Pooled it
- The immune-modulatory potential of helminth-derived proteins in cellular models of inflammation: a systematic review with cross-study quantitative data analysis.Scientific reports · 2026Pooled it
- A systematic review and meta-analysis on the global prevalence of helminthic parasites among schoolchildren: a public health concern.BMC public health · 2025Pooled it
- Community-wide deworming strategies to reduce high hookworm burden in endemic communities: Results from a cluster randomized trial in Southern India.PLoS neglected tropical diseases · 2026Trial
- Review
- Phage-display immunoprecipitation sequencing reveals distinct antibody repertoire patterns across rural and urban populations.iScience · 2026Article
- Gastrointestinal helminth infections in cattle and buffalo from small-scale farms in Phayao Province, Northern Thailand.Tropical animal health and production · 2026Article
- Prevalence and risk factors of intestinal parasitism among schoolchildren in the municipality of Banfora, Burkina Faso.Food and waterborne parasitology · 2026Article
- Estimation of the global burden of tungiasis in endemic countries using a disability adjusted life-years modelling approach.BMC global and public health · 2026Article
- A Paired-Marker Framework for Interpreting Anti-Pathogens (Basel, Switzerland) · 2026Article
- Proteomic reprogramming of ileal epithelial cells during homologous superimposed intestinal trematode infection reveals coordinated restoration of intestinal homeostasis.PLoS neglected tropical diseases · 2026Article
- Prevalence and determinants of deworming uptake among under-five children in Tanzania: evidence from the Tanzania Demographic and Health Survey 2022.Tropical medicine and health · 2026Article
- Surveillance and sociodemographic risk profiling of human soil-transmitted helminth infections in Gabon, Central Africa.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2026Article
- Prevalence of multiple human intestinal parasites across diverse environments in Madagascar.PLoS neglected tropical diseases · 2026Article
- Towards host-directed therapy: The role of matrix metalloproteinases in the immunopathogenesis of tuberculosis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026Review
- Post-market surveillance of albendazole tablet brands in Kenya: Implications for deworming programs and clinical outcomes.PLoS neglected tropical diseases · 2026Article
- Heavy burden of soil-transmitted helminth infections in a remote and impoverished indigenous community of Honduras revealed by real time polymerase chain reaction.Infectious diseases of poverty · 2026Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
backgroundSoil-transmitted helminth (STH) infections can cause a significant disease burden. It is estimated that 1.5 billion people worldwide are infected with STHs, primarily in tropical and subtropical regions. This study aimed to assess the distribution of the global burden and trend of STH infections from 1990 to 2021.
methodsWe retrieved data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 on the age-standardized rates (ASRs) of prevalence and disability-adjusted life-years (DALYs) of STH infections for all age groups in 204 countries and territories from 1990 to 2021. The ASRs of prevalence and DALYs by age, gender, and socio-demographic index (SDI) were calculated to quantify the spatial distribution and temporal trend. Spearman correlation analysis was used to examine the relationship between ASR and SDI.
resultsIn 2021, there were an estimated 642.72 million cases and 1.38 million DALYs caused by STH infections worldwide. The age-standardized prevalence rate (ASPR) of STH infections was 8429.89 [95% uncertainty interval (UI): 7697.23, 9362.18 ] per 100,000 population globally. The ASPR of STH infections varied across 21 geographic regions in 2021, being mainly prevalent in most African and Latin American locations. The prevalence was higher in the groups of 5-19 years, especially the group of 5-9 years with the ASPR of 16,263 (95% UI: 14,877.06, 18,003.49) and ASR of DALYs of 40.69 (95% UI: 25.98, 60.91) per 100,000. The ASPR of STH infections showed an obvious decreasing trend worldwide (estimated annual percent change = - 4.03, 95% confidence interval: - 4.13, - 3.93) with variations in different species infections during the study years. At the regional level, the ASR of STH infections prevalence (r = - 0.8807, P < 0.0001) and DALYs (r = - 0.9069, P < 0.0001) were negatively correlated with SDI .
conclusionsSTH infections remain a public health problem in 2021, particularly in regions such as the middle parts of Africa and Americas, and in the 5-19 age populations. The reduction in the rate of prevalence and the loss of DALYs are negatively correlated with the increase in SDI. Enhancing political commitment, providing accurate preventive chemotherapy, and advancing techniques for surveillance and mapping systems are essential to achieve the target of ending STH infections as a public health problem by 2030.
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