Evidence map›Paper›PMID 39443873›Full record

ArticleBMC geriatrics2024

Efficacy of a combined exercise and nutrition intervention study for outpatients with possible sarcopenia in community-based primary care clinics (ENdSarC): study protocol for a multicenter single-blinded randomized controlled trial.

Woohyuk Ji, Daehyun Lee, Minjin Kim, Nahyun Lim, Jae-Young Lim, Jae Uk Baek, Sungwouk Kim, Choong Hyung Lee, Miji Kim, Chang Won Won

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06049914 (Combined Exercise and Nutrition Intervention for Possible Sarcopenia Among Community-dwelling Older Adults in Primary Care), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06049914 naunknown statusnot on this map

Combined Exercise and Nutrition Intervention for Possible Sarcopenia Among Community-dwelling Older Adults in Primary Care: A Randomized Controlled Trial

TypeinterventionalSponsorKyunghee University Medical CenterRan2023 to 2024Enrolled94ConditionsSarcopeniaArmsExperimental group
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Woohyuk Ji *Department of Family Medicine, College of Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Daehyun Lee *KHU-KIST Department of Converging Science and Technology, Graduate School, Kyung Hee University, Seoul, 02447, Republic of Korea.
Minjin KimDepartment of Family Medicine, College of Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Nahyun LimDepartment of Precision Medicine, Graduate School, Kyung Hee University, Seoul, 02447, Republic of Korea.
Jae-Young LimDepartment of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea.
Jae Uk BaekDepartment of Family Medicine, Dongdong Family Clinic, Seoul, 01384, Republic of Korea.
Sungwouk KimDepartment of Surgery, Dongbu Hanil Surgery Clinic, Seoul, 01325, Republic of Korea.
Choong Hyung LeeDepartment of Family Medicine, Seoul Bom Union Clinic, Seoul, 01006, Republic of Korea.
Miji KimDepartment of Health Sciences and Technology, College of Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. mijiak@khu.ac.kr.
Chang Won WonElderly Frailty Research Center, Department of Family Medicine, College of Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. chunwon@khmc.or.kr.

Funding

Patient-Centered Clinical Research Coordinating Center HI19C0481
6 · The paper itself

Abstract

backgroundSarcopenia is a geriatric disease characterized by loss of muscle mass and strength. Although combined exercise and nutrition intervention are known to be effective for sarcopenia, clinical trials involving outpatients with sarcopenia in primary care are scarce. We describe a protocol for a trial to examine the effects of a 12-week combined exercise and nutrition intervention in Korean older adults with possible sarcopenia in community-based primary care.

methodsThis multicenter, randomized, controlled trial will include 94 community-dwelling older outpatients aged 65-85 years with possible sarcopenia (47 participants in the intervention and control groups each). Resistance exercises, which incorporate concentric and eccentric exercises, will consist of an introductory phase (3 weeks: twice-weekly supervised exercise sessions and once-weekly home exercises; contraction exercises), an expanded phase (3 weeks: twice-weekly supervised exercise sessions and once-weekly home exercises; eccentric exercises), and a maintenance phase (6 weeks: once-weekly supervised exercise sessions and twice-weekly home exercises; power/eccentric exercises). Nutritional supplementation will be provided according to the nutritional status of the participants using a Mini-Nutritional Assessment. Participants will be assessed at baseline, 12 and 24 weeks, and the primary outcome will be the 5-times chair stand test results. DISCUSSION: To the best of our knowledge, this will be the first clinical trial to evaluate the efficacy of a combined exercise and nutritional supplementation intervention in older outpatients with possible sarcopenia in community-based primary care clinics. These findings will provide new insights to clinicians regarding the long-term usability for doctors and outpatients with possible sarcopenia in community-based primary care.

trial registrationThis trial was prospectively registered at ClinicalTrials.gov on September 16, 2023 (registration number: NCT06049914).

Indexed as

Exercise TherapyPrimary Health CareSarcopeniaAgedAged, 80 and overFemaleHumansMaleMulticenter Studies as TopicOutpatientsRandomized Controlled Trials as TopicSingle-Blind MethodCombined exercise-nutritionCommunity-basedInterventionOlder adultsOutpatientsPrimary care

Identifiers

PMID39443873
PMCPMC11515764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.