Evidence map›Paper›PMID 39443855›Full record

Trial reportBMC pregnancy and childbirth2024

Effect of antenatal use of high energy nutritional supplements on cardio metabolic risk markers in underweight primi gravidas; a randomized controlled trial.

Kalsoom Tariq, Hafsa Zafar, Nabila Sher, Bela Inayat, Mashal Zafar, Fozia Fozia, Sofia Islam, Sadia Fatima, Ijaz Ahmad, Mohamed Mohany and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kalsoom TariqBiochemistry Department, Khyber Girls Medical College, Peshawar, Pakistan.
Hafsa ZafarBiochemistry Department, Khyber Medical University, Peshawar, Pakistan.
Nabila SherBiochemistry Department, Khyber Girls Medical College, Peshawar, Pakistan.
Bela InayatBiochemistry Department, Khyber Girls Medical College, Peshawar, Pakistan.
Mashal ZafarBiochemistry Department, Khyber Medical University, Peshawar, Pakistan.
Fozia FoziaDepartment of Biochemistry, KMU Institute of Dental Sciences, Kohat, KP, 26000, Pakistan. drfoziazeb@yahoo.com.ORCID http://orcid.org/0000-0002-4554-7427
Sofia IslamBiochemistry Department, Khyber Medical University, Peshawar, Pakistan.
Sadia FatimaBiochemistry Department, Khyber Medical University, Peshawar, Pakistan. drsadiafatima@gmail.com.
Ijaz AhmadDepartment of Chemistry, Kohat University of Science and Technology, Kohat, 26000, Pakistan.
Mohamed MohanyDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 55760, Riyadh, 11451, Saudi Arabia.
Salim S Al-RejaieDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 55760, Riyadh, 11451, Saudi Arabia.
Mingkun ZhuJiangsu Key Laboratory of Sericultural Biology and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China.

Funding

Khyber Medical University Publication Fund (No. DIR/ORIC/Ref/24/00076)King Saud University Researchers Supporting Project (RSPD2024R758)
6 · The paper itself

Abstract

backgroudPregnancy is a state of increased metabolic demand, and poor maternal nutrition can exacerbate these changes, potentially increasing the risk of cardiometabolic disorders.This study is significant as it investigates the effect of high energy nutritional supplements on cardio metabolic risk markers in underweight primigravidas. METHODOLOGY: A single blinded randomized controlled trial was conducted from April 2018- August 2019 among the Pakistani tertiary care facilities of Khyber Pakhtunkhwa. A total of thirty six participants were randomized into two groups receiving either high energy nutritional supplement 'MAAMTA' or Placebo. They were instructed to take Placebo/Supplement alongside to their regular prenatal care and food from their first antenatal visit till a week postnatally. Anthropometric measurements and blood samples for biochemical parameters insulinlevels, fasting blood glucose & lipid profile were taken at baseline visit, between 16 and 20 weeks gestation and a post natal visit.

resultsThe two-way repeated measures ANOVA showed that there was a highly significant time effect on participant's Insulin level (F (1.8, 53.6) = 10.64, P < 0 0.000, ηp

conclusionSupplementation with high energy nutritional supplements may improve insulin levels and insulin sensitivity in underweight primigravidas.

trial registrationhttps://www. CLINICALTRIALS: gov ClinicalTrials.gov Identifier: ISRCTN 10088578. Registered on 27 March 2018. https://www.isrctn.com/ISRCTN10088578 .

Indexed as

Dietary SupplementsThinnessAdultBiomarkersBlood GlucoseCardiometabolic Risk FactorsFemaleGravidityHumansInsulinInsulin ResistancePakistanPregnancyPregnancy ComplicationsPrenatal CareSingle-Blind MethodBiomarkersBlood GlucoseInsulinCardio metabolic risk factorsHigh energy nutritional supplementsInsulin resistancePrimigravida

Identifiers

PMID39443855
PMCPMC11515724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.