Evidence map›Paper›PMID 39443798›Full record

ArticleNature2024

Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin.

Adrianna M Turner, Lucy Li, Ian R Monk, Jean Y H Lee, Danielle J Ingle, Stephanie Portelli, Norelle L Sherry, Nicole Isles, Torsten Seemann, Liam K Sharkey and 19 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Reducing the Risk of Overt Hepatic Encephalopathy Recurrence: A Narrative Review.Journal of clinical and translational hepatology · 2026
    Review
  8. Review
  9. Article
  10. Non-susceptibility ofMicrobiology spectrum · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. BeyondAntimicrobial agents and chemotherapy · 2026
    Article
  19. Disease Modulating Agents in Cirrhosis.Clinics in liver disease · 2026
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Adrianna M TurnerDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0009-0000-5840-7119
Lucy LiDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Ian R MonkDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0001-6982-8074
Jean Y H LeeDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0001-5751-8503
Danielle J IngleDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0003-0707-6537
Stephanie PortelliComputational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.ORCID 0000-0003-3515-4301
Norelle L SherryDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Nicole IslesDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Torsten SeemannDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0001-6046-610X
Liam K SharkeyDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0001-9324-8678
Calum J WalshDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Gavin E ReidSchool of Chemistry, The University of Melbourne, Melbourne, Victoria, Australia.
Shuai NieMelbourne Mass Spectrometry and Proteomics Facility, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Victoria, Australia.
Bart A EijkelkampMolecular Sciences and Technology, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.ORCID 0000-0003-0179-8977
Natasha E HolmesDepartment of Infectious Diseases & Immunology, Austin Health, Melbourne, Victoria, Australia.
Brennan CollisDepartment of Infectious Diseases & Immunology, Austin Health, Melbourne, Victoria, Australia.
Sara VogrinDepartment of Infectious Diseases & Immunology, Austin Health, Melbourne, Victoria, Australia.
Andreas HiergeistInstitute of Clinical Microbiology and Hygiene, University Medical Center, Regensburg, Germany.
Daniela WeberDepartment of Internal Medicine III, Hematology and Medical Oncology, University Medical Center, Regensburg, Germany.
Andre GessnerInstitute of Clinical Microbiology and Hygiene, University Medical Center, Regensburg, Germany.
Ernst HollerDepartment of Internal Medicine III, Hematology and Medical Oncology, University Medical Center, Regensburg, Germany.
David B AscherComputational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.ORCID 0000-0003-2948-2413
Sebastian DucheneDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0002-2863-0907
Nichollas E ScottDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0003-2556-8316
Timothy P StinearDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0003-0150-123X
Jason C KwongDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Claire L GorrieDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0002-2637-2529
Benjamin P HowdenDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia. bhowden@unimelb.edu.au.ORCID 0000-0003-0237-1473
Glen P CarterDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia. glen.carter@unimelb.edu.au.ORCID 0000-0002-7306-9362

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug-resistant bacterial pathogens like vancomycin-resistant Enterococcus faecium (VREfm) are a critical threat to human health

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisDaptomycinDrug Resistance, Multiple, BacterialEnterococcus faeciumHepatic EncephalopathyRifaximinAnimalsDNA-Directed RNA PolymerasesFemaleGram-Positive Bacterial InfectionsHumansLiver CirrhosisMiceMice, Inbred C57BLMutationAnti-Bacterial AgentsDaptomycinDNA-Directed RNA PolymerasesRifaximinVancomycin

Identifiers

PMID39443798
PMCPMC11602712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.