ArticleNature2024
Differentiation fate of a stem-like CD4 T cell controls immunity to cancer.
Erratum issuedAbstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed.
- Dynamic immune profiling predicts response to radiation plus anti-PD-1 therapy in oligometastatic renal cell carcinoma.Nature communications · 2026Trial
- Article
- Targeting BCL9/BCL9L enhances CD4Acta pharmacologica Sinica · 2026Article
- H3.3 chaperone Hira primes the effector program and function of regulatory T cells.Science advances · 2026Article
- Molecular heterogeneity and clonal origin of CCR8Nature communications · 2026Article
- Clonal sharing and plasticity of follicular CD4 + T cells across lymph nodes and tumors in non-small cell lung cancer.Nature communications · 2026Article
- Single-Cell RNA Sequencing Reveals T-Cell Metabolic Activation and SGPL1 as a Candidate Predictor of PD-1 Resistance in Urothelial Carcinoma.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Hypoxia shapes both therapeutic response and resistance in metastatic clear cell renal cell carcinoma.Cancer cell · 2026Article
- Tumor-draining lymph nodes shape the tumor microenvironment through enrichment of tumor-reactive effector-exhausted CD8Signal transduction and targeted therapy · 2026Article
- CD4Science (New York, N.Y.) · 2026Article
- Article
- Immune Landscape and Tumour Heterogeneity in Ovarian Cancer: Insights From Single-Cell RNA Sequencing.Journal of cellular and molecular medicine · 2026Review
- FAP-CD40 and PD1-IL2v combination therapy reprograms immunologically cold tumors through de novo intratumoral T cell-dendritic cell clusters.Journal for immunotherapy of cancer · 2026Article
- TOX drives CD4Nature immunology · 2026Article
- Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer.Science immunology · 2026Article
- Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection.Nature immunology · 2026Article
- Preclinical efficacy of combination therapy with allogeneic induced pluripotent stem cell-derived invariant natural killer T and α-galactosylceramide-pulsed antigen-presenting cells.Stem cell research & therapy · 2026Article
- Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPVbioRxiv : the preprint server for biology · 2026Article
- Specific depletion of TIGITJournal for immunotherapy of cancer · 2026Article
- High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion.Nature communications · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
14 authors.
Maria A CardenasDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Nataliya ProkhnevskaDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Ewelina SobierajskaDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Petra GregorovaDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Christopher B MedinaEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Rajesh M ValanparambilEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Rachel GreenwaldDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-3139-5079
Luke DelBalzoDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Mehmet Asim BilenEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Shreyas S JoshiDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Vikram M NarayanDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-3731-4209
Viraj A MasterDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Martin G SandaDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Haydn T KissickDepartment of Urology, Emory University School of Medicine, Atlanta, GA, USA. haydn.kissick@emory.edu.ORCID 0000-0001-7624-5598
Funding
Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0MProstate Cancer Biomarker and Imaging Validation Alliance: Emory University, University of Alabama Birmingham, and University of Texas SouthwesternU01CA113913 · NCI · EMORY UNIVERSITY · PI Martin G. Sanda · 2005 to 2026
$16.4MGenetic Mechanisms Controlling Kidney Cancer Immune EscapeR01CA280069 · NCI · EMORY UNIVERSITY · PI Haydn Kissick · 2024 to 2026
$1.2MIllumina NovaSeq 6000 High Throughput DNA Sequencer for Emory UniversityS10OD026799 · OD · EMORY UNIVERSITY · PI BOSINGER, STEVEN EDWARD · 2019 to 2019
$985kNCI NIH HHS R01 CA280069NCI NIH HHS U01 CA113913NIH HHS P51 OD011132NIH HHS S10 OD026799
Abstract
The T cell response to cancer controls disease progression and response to immunotherapy
Indexed as
CD4-Positive T-LymphocytesCell DifferentiationImmunotherapyKidney NeoplasmsStem CellsAnimalsCD8-Positive T-LymphocytesCell Self RenewalFemaleHepatocyte Nuclear Factor 1-alphaHumansInterferon-gammaLymph NodesMaleMiceMice, Inbred C57BLHepatocyte Nuclear Factor 1-alphaHNF1A protein, humanInterferon-gammaPDCD1 protein, humanProgrammed Cell Death 1 ReceptorT-bet Transcription FactorT-Box Domain Proteins
Identifiers
PMID
39443797What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.