ReviewNature protocols2025
Outcome devaluation as a method for identifying goal-directed behaviors in rats.
Review in Nature protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Does time pressure reveal habits? Divergent results from outcome devaluation and response remapping paradigms.Cognitive, affective & behavioral neuroscience · 2026Article
- Early-Stage Corticostriatal Hyperactivity Impairs Cognitive Flexibility Alongside Striatal Cholinergic Dysfunction in an Alzheimer's Disease Model.Nature communications · 2026Article
- Article
- Assessing behavioral control across the adult lifespan using a novel outcome revaluation task.Scientific reports · 2025Article
- Article
- Stimulus conditions that promote habitual control.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Goal-directed behaviors allow animals to act to satisfy needs and desires. The outcome devaluation task is an effective method for identifying goal-directed behaviors and distinguishing these from other types of behavior. Rats can be trained to lever-press for one or multiple distinct food rewards. During testing, the previously earned food-or a control food for comparison-is devalued by allowing the animal to freely feed on it until they are sated before testing lever-press performance under extinction conditions (no rewards are delivered). Behavior that adapts to reflect the new value of the outcome is considered goal-directed, whereas behavior that continues as in previous training despite the change in outcome value, is not. As more research groups have used this task, variability in the procedures used has increased. Here, we provide a reliable procedure for conducting the outcome devaluation task with appropriate controls. We describe the most common variants of the task and control conditions and discuss troubleshooting measures such as outcome pre-exposure, habituation to pre-feeding chambers and attention to animals' hunger levels. The method outlined can be executed in ~2 weeks including training (~8 d) and testing (1-4 d) by researchers who are familiar with performing behavioral tasks in laboratory rodents, although longer training may be considered for those who are interested in observing habitual control of behavior. This protocol should facilitate the comparison of results from different studies and laboratories, while allowing flexibility in the application of the outcome devaluation task to different research questions.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.