Evidence map›Paper›PMID 39443624›Full record

ArticleNPJ digital medicine2024

Development and assessment of a machine learning tool for predicting emergency admission in Scotland.

James Liley, Gergo Bohner, Samuel R Emerson, Bilal A Mateen, Katie Borland, David Carr, Scott Heald, Samuel D Oduro, Jill Ireland, Keith Moffat and 10 more

Erratum issuedAbstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

James Liley *Department of Mathematical Sciences, Durham University, Durham, UK. james.liley@durham.ac.uk.ORCID http://orcid.org/0000-0002-0049-8238
Gergo Bohner *Alan Turing Institute, London, UK.
Samuel R EmersonDepartment of Mathematical Sciences, Durham University, Durham, UK.
Bilal A MateenAlan Turing Institute, London, UK.
Katie BorlandPublic Health Scotland (PHS), Edinburgh, UK.
David CarrPublic Health Scotland (PHS), Edinburgh, UK.
Scott HealdPublic Health Scotland (PHS), Edinburgh, UK.
Samuel D OduroPublic Health Scotland (PHS), Edinburgh, UK.
Jill IrelandPublic Health Scotland (PHS), Edinburgh, UK.
Keith MoffatPublic Health Scotland (PHS), Edinburgh, UK.
Rachel PorteousPublic Health Scotland (PHS), Edinburgh, UK.
Stephen RiddellPublic Health Scotland (PHS), Edinburgh, UK.
Simon RogersNHS National Services Scotland, Edinburgh, UK.ORCID http://orcid.org/0000-0003-3578-4477
Ioanna ThomaAlan Turing Institute, London, UK.
Nathan CunninghamAlan Turing Institute, London, UK.ORCID http://orcid.org/0000-0002-2663-519X
Chris HolmesAlan Turing Institute, London, UK.
Katrina PayneAlan Turing Institute, London, UK.
Sebastian J VollmerAlan Turing Institute, London, UK.
Catalina A VallejosAlan Turing Institute, London, UK. catalina.vallejos@ed.ac.uk.ORCID http://orcid.org/0000-0003-3638-1960
Louis J M AslettDepartment of Mathematical Sciences, Durham University, Durham, UK. louis.aslett@durham.ac.uk.ORCID http://orcid.org/0000-0003-2211-233X

Funding

RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/R513039/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/T001569/1Wellcome Trust
6 · The paper itself

Abstract

Emergency admissions (EA), where a patient requires urgent in-hospital care, are a major challenge for healthcare systems. The development of risk prediction models can partly alleviate this problem by supporting primary care interventions and public health planning. Here, we introduce SPARRAv4, a predictive score for EA risk that will be deployed nationwide in Scotland. SPARRAv4 was derived using supervised and unsupervised machine-learning methods applied to routinely collected electronic health records from approximately 4.8M Scottish residents (2013-18). We demonstrate improvements in discrimination and calibration with respect to previous scores deployed in Scotland, as well as stability over a 3-year timeframe. Our analysis also provides insights about the epidemiology of EA risk in Scotland, by studying predictive performance across different population sub-groups and reasons for admission, as well as by quantifying the effect of individual input features. Finally, we discuss broader challenges including reproducibility and how to safely update risk prediction models that are already deployed at population level.

Identifiers

PMID39443624
PMCPMC11499905

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.