Evidence map›Paper›PMID 39443541›Full record

ArticleScientific reports2024

Development of a colloidal gold immunochromatographic test strip for detecting the smooth Brucella.

Qi Wu, Xiaohan Guo, Qianhan Huang, Yujia Xie, Liping Guo, Xiangdong Yang, Mingjun Sun, Dehui Yin

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Rapid serological detection of smoothFrontiers in cellular and infection microbiology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qi Wu *School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Xiaohan Guo *School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Qianhan Huang *School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Yujia XieSchool of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Liping GuoSchool of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Xiangdong YangSchool of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China. 100000119001@xzhmu.edu.cn.
Mingjun SunLaboratory of Zoonoses, Animal Health and Epidemiology Center, No.369 Nanjing Road, 266032, Qingdao, China. sunmingjun@cahec.cn.
Dehui YinSchool of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China. yindh16@xzhmu.edu.cn.

Funding

Medical Research Program of Jiangsu Commission of Health Z2023080Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX23-2963Xuzhou Science and Technology Bureau KC23306
6 · The paper itself

Abstract

Brucellosis, caused by Gram-negative Brucella, spreads in human and animal populations through contact with infected animals and products. Developing a rapid and sensitive detection technology for pathogen is crucial to reduce the risk of this disease transmitting between animal populations and to humans. We produced a monoclonal antibody LPS-6B5, which shows high affinity to LPS and limited cross-reactivity with other bacteria. Based on LPS-6B5, a colloidal gold immunochromatographic assay (GICA) was developed which demonstrates high sensitivity and specificity in detecting cultured B. melitensis, B. abortus and B. suis. The Gold Immunochromatographic Assay (GICA) strips exhibited the most sensitive detection limits, with a value of 7.8125 × 10

Indexed as

BrucellaBrucellosisChromatography, AffinityGold ColloidAnimalsAntibodies, MonoclonalBrucella abortusBrucella melitensisBrucella suisHumansImmunoassayLipopolysaccharidesReagent StripsSensitivity and SpecificityAntibodies, MonoclonalGold ColloidLipopolysaccharidesReagent StripsColloidal gold immunochromatographic assay (GICA)LPSMonoclonal antibodyRapid testSmooth Brucella

Identifiers

PMID39443541
PMCPMC11500340

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.