Evidence map›Paper›PMID 39443450›Full record

ArticleNature communications2024

Dominant immune tolerance in the intestinal tract imposed by RelB-dependent migratory dendritic cells regulates protective type 2 immunity.

Anna-Lena Geiselhöringer, Daphne Kolland, Arisha Johanna Patt, Linda Hammann, Amelie Köhler, Luisa Kreft, Nina Wichmann, Miriam Hils, Christiane Ruedl, Marc Riemann and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Intestinal muscularis in health and disease.Communications biology · 2026
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Anna-Lena GeiselhöringerCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0009-0000-3054-8446
Daphne KollandCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.
Arisha Johanna PattCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0000-0001-8956-2373
Linda HammannDivision of Clinical Pharmacology, LMU University Hospital, LMU, Munich, Germany.
Amelie KöhlerCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.
Luisa KreftCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0009-0002-9259-9729
Nina WichmannCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0009-0006-5652-0859
Miriam HilsDepartment of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Christiane RuedlSchool of Biological Sciences, Nanyang Technological University Singapore, Singapore, Singapore.ORCID 0000-0002-5599-6541
Marc RiemannLeibniz Institute on Aging, Fritz Lipmann Institute, 07745, Jena, Germany.
Tilo BiedermannDepartment of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich, Munich, Germany.ORCID 0000-0002-5352-5105
David AnzDivision of Clinical Pharmacology, LMU University Hospital, LMU, Munich, Germany.
Andreas DiefenbachLaboratory of Innate Immunity, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, 12203, Berlin, Germany.ORCID 0000-0002-9176-9530
David VoehringerDepartment of Infection Biology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, 91054, Germany.ORCID 0000-0001-6650-0639
Carsten B Schmidt-WeberCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0000-0002-3203-8084
Tobias StraubBioinformatics Core Unit, Biomedical Center, Ludwig-Maximilians-University, 82152, Planegg, Germany.ORCID 0000-0002-0547-0453
Maria PasztoiCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0000-0002-0481-4138
Caspar OhnmachtCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany. caspar.ohnmacht@helmholtz-munich.de.ORCID 0000-0002-6887-8819

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 395357507 - CRC1371 TP07Deutsche Forschungsgemeinschaft (German Research Foundation) 490846870 - TRR355/1 TP05Deutsche Forschungsgemeinschaft (German Research Foundation) 490846870 - TRR355/1 TPB02Deutsche Forschungsgemeinschaft (German Research Foundation) OH 282/1-2EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 716718
6 · The paper itself

Abstract

Dendritic cells (DCs) are crucial for initiating protective immune responses and have also been implicated in the generation and regulation of Foxp3

Indexed as

Dendritic CellsImmune ToleranceMice, Inbred C57BLMice, KnockoutT-Lymphocytes, RegulatoryTranscription Factor RelBAnimalsCell DifferentiationCell MovementChemokine CCL22Forkhead Transcription FactorsIntestinal MucosaIntestine, SmallMiceStrongylida InfectionsTh2 CellsChemokine CCL22Forkhead Transcription FactorsFoxp3 protein, mouseRelb protein, mouseTranscription Factor RelB

Identifiers

PMID39443450
PMCPMC11500181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.