Evidence map›Paper›PMID 39443369›Full record

ArticleArchives of microbiology2024

Antibacterial effects and mechanisms of quercetin-β-cyclodextrin complex mediated photodynamic on Escherichia coli O157:H7.

Tao Liu, Yuzhang Zhu, Jiahui Wang, Xiangyu Hong, Mi Liu, Chaonan Kong, Rui Zhou, Xianke Li, Lifang Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Phytochemicals Controlling EnterohemorrhagicInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tao Liu *Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, 158 Daxue West Road, Xixiangtang District, Nanning, Guangxi Province, 530006, China.
Yuzhang Zhu *Guangxi Key Laboratory of Polysaccharide Materials and Modification, School of Marine and Biotechnology, Guangxi Minzu University, Nanning, 530006, China.
Jiahui WangKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, 158 Daxue West Road, Xixiangtang District, Nanning, Guangxi Province, 530006, China.
Xiangyu HongKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, 158 Daxue West Road, Xixiangtang District, Nanning, Guangxi Province, 530006, China.
Mi LiuKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, 158 Daxue West Road, Xixiangtang District, Nanning, Guangxi Province, 530006, China.
Chaonan KongKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, 158 Daxue West Road, Xixiangtang District, Nanning, Guangxi Province, 530006, China.
Rui ZhouGuangxi Key Laboratory of Polysaccharide Materials and Modification, School of Marine and Biotechnology, Guangxi Minzu University, Nanning, 530006, China.
Xianke LiGuangxi Key Laboratory of Polysaccharide Materials and Modification, School of Marine and Biotechnology, Guangxi Minzu University, Nanning, 530006, China.
Lifang YangKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, 158 Daxue West Road, Xixiangtang District, Nanning, Guangxi Province, 530006, China. yanglf1990@163.com.ORCID http://orcid.org/0000-0002-7563-7765

Funding

2023 Guangxi University for Nationalities Graduate Education Innovation Plan Project gxun chxs2024110Science and Technology Major Project of Guangxi Guike AB21196020
6 · The paper itself

Abstract

Quercetin is a natural flavonoid with antioxidant, anti-inflammatory, and antibacterial properties. This work aimed to formulate quercetin-cyclodextrin microcapsules (QT-β-CD) while examining their photodynamic antibacterial effects and underlying mechanisms in detail. Characterization of the QT-β-CD was conducted using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and thermogravimetric analysis (TGA). The bacteriostatic effects of UV-A irradiation on Escherichia coli O157:H7 (E. coli O157:H7) were investigated. The photodynamic impact of QT-β-CD was assessed by analyzing hydrogen peroxide (H₂O₂) production. The antimicrobial activity was further elucidated through examinations of cell membrane integrity, protein damage, changes in cellular motility, biofilm formation, and extracellular polysaccharide reduction. The effect of QT-β-CD on LuxS and motA gene expression in E. coli O157:H7 was investigated by RT-qPCR. The findings demonstrated that QT-β-CD exhibited potent photodynamic properties and functioned as an efficient photosensitizer, causing substantial damage to E. coli O157:H7 cells. These results underscore the potential of quercetin as an antimicrobial agent for food preservation.

Indexed as

Anti-Bacterial Agentsbeta-CyclodextrinsEscherichia coli O157QuercetinBiofilmsHydrogen PeroxideMicrobial Sensitivity TestsPhotosensitizing AgentsSpectroscopy, Fourier Transform InfraredUltraviolet RaysAnti-Bacterial Agentsbeta-CyclodextrinsHydrogen PeroxidePhotosensitizing AgentsQuercetinMicroencapsulationPhotodynamic antibacterialQuercetinΒ-cyclodextrin

Identifiers

PMID39443369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.