Evidence map›Paper›PMID 39443186›Full record

ReviewBritish journal of anaesthesia2025

Gastric emptying in pregnancy and its clinical implications: a narrative review.

Jacob Lawson, Ryan Howle, Petar Popivanov, Jas Sidhu, Camilla Gordon, Maria Leong, Desire Onwochei, Neel Desai

Abstract readReview
In one paragraph

Review in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Biological sex differences in pharmacokinetics and adverse drug reactions.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacob LawsonDepartment of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Ryan HowleDepartment of Anaesthesia, Rotunda Hospital, Dublin, Ireland.
Petar PopivanovDepartment of Anaesthesia, Coombe Hospital, Dublin, Ireland.
Jas SidhuDepartment of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Camilla GordonDepartment of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Maria LeongDepartment of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Desire OnwocheiDepartment of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK; King's College London, London, UK.
Neel DesaiDepartment of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK; King's College London, London, UK. Electronic address: Neel.Desai@gstt.nhs.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed gastric emptying increases the risk of pulmonary aspiration during anaesthesia for Caesarean delivery. Our aim in conducting this narrative review was to consider the effect of pregnancy on gastric emptying. The indices of gastric emptying after liquids, solids, or both and when fasted in the various trimesters of pregnancy, at the time of Caesarean delivery, in labour, and the postpartum period were assessed. We considered 32 observational studies, one nonrandomised controlled study, and 22 randomised controlled trials. The evidence indicates that, compared with the nonpregnant state, gastric emptying is decreased in the first but not the second and third trimesters. Before elective Caesarean delivery, carbohydrate drink or tea with milk leads to no difference in gastric cross-sectional area at 2 h relative to fasting or water. Following a standard fast for elective Caesarean delivery, patients may still have high-risk gastric contents. Compared with the nonpregnant state and third trimester, gastric emptying is delayed in labour, although the choice of analgesia has modifying effects. Systemic opioids delay gastric emptying. Epidural analgesia increases gastric emptying, but not back to baseline. Intrathecal analgesia delays gastric emptying relative to epidural analgesia. Women in labour who have eaten solids in the last 8 h still have high-risk gastric contents present in the stomach. The evidence with respect to the postpartum period is conflicting. In conclusion, inconsistencies in the literature reflect the unpredictability of gastric emptying in pregnancy and underline the potential value of gastric ultrasound in women who are pregnant.

Indexed as

Cesarean SectionGastric EmptyingAnesthesia, ObstetricalFemaleHumansPostpartum PeriodPregnancyfastinggastric emptyingpostpartumpregnancyultrasound

Identifiers

PMID39443186
PMCPMC11718367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.