ArticleAJNR. American journal of neuroradiology2025
Automated Quantification of Cerebral Microbleeds in SWI: Association with Vascular Risk Factors, White Matter Hyperintensity Burden, and Cognitive Function.
Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Accuracy of Deep Learning in Detecting Cerebral Microbleeds: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- Exploration of heterogeneity in risk factors associated with imaging subtypes of white matter hyperintensities on fluid-attenuated inversion recovery magnetic resonance imaging.Frontiers in neurology · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
background and purposeThe amount and distribution of cerebral microbleeds (CMB) are important risk factors for cognitive impairment. Our objective was to train and validate a deep learning (DL)-based segmentation model for cerebral microbleeds (CMBs) on SWI and to find associations among CMB, cognitive impairment, and vascular risk factors. MATERIALS AND
methodsParticipants in this single-institution retrospective study underwent brain MRI to evaluate cognitive impairment between January and September 2023. For training the DL model, the nnU-Net framework was used without modifications. The performance of the DL model was evaluated on independent internal and external validation data sets. Linear regression analysis was used to find associations among log-transformed CMB numbers, cognitive function (Mini-Mental Status Examination [MMSE]), white matter hyperintensity (WMH) burden, and clinical vascular risk factors (age, sex, hypertension, diabetes, lipid profiles, and body mass index).
resultsTraining of the DL model (
conclusionsThe DL model showed a robust segmentation performance for CMB. In all distributions, CMB had significant positive associations with WMH burden. Increased WMH burden and CMB numbers were associated with decreased cognitive function.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.