Evidence map›Paper›PMID 39442933›Full record

ArticleVox sanguinis2025

An ecosystem of interconnected technologies to increase efficiencies in blood establishments: The example of the Blood and Tissue Bank of Aragón, Spain.

Ana Isabel Pérez Aliaga, Irene Ayerra, Marcia Cardoso, Fernando Puente, Alfonso Aranda, José María Domingo, Rosa Plantagenet-Whyte

Abstract read
In one paragraph

Article in Vox sanguinis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Isabel Pérez AliagaBlood and Tissues Bank of Aragón (BTBA), Zaragoza, Spain.ORCID https://orcid.org/0009-0002-7796-9541
Irene AyerraHemotic, Olite, Spain.
Marcia CardosoTerumo Blood and Cell Technologies, Zaventem, Belgium.ORCID https://orcid.org/0000-0002-4951-4091
Fernando PuenteBlood and Tissues Bank of Aragón (BTBA), Zaragoza, Spain.
Alfonso ArandaBlood and Tissues Bank of Aragón (BTBA), Zaragoza, Spain.
José María DomingoBlood and Tissues Bank of Aragón (BTBA), Zaragoza, Spain.
Rosa Plantagenet-WhyteBlood and Tissues Bank of Aragón (BTBA), Zaragoza, Spain.

Funding

The development of this manuscript was funded by Terumo Blood and Cell Technologies, which covered the costs related to medical writing and manuscript coordination services. The content of this manuscript reflects the independent views of the authors and is not influenced by the funding organization.
6 · The paper itself

Abstract

BACKGROUND AND

objectivesBlood establishments face environmental, financial, demographic and societal challenges that may impair sustainable blood supply to patients. This study presents the technologies (devices and software) assembled in a global ecosystem implemented by the Blood and Tissue Bank of Aragón (BTBA), Spain, over the last decade to overcome these challenges. MATERIALS AND

methodsDescriptive yearly activity data (2013-2023) of BTBA were retrospectively collected to evaluate the impact of different technologies on blood processing efficiency, focusing on the production of blood components (red blood cell concentrates [RCCs], platelet concentrates [PCs]) and plasma. Operator satisfaction about the technologies introduced in daily routine work was also monitored.

resultsBetween 2013 and 2023, the annual production decreased by 16.0% for RCCs and increased by 13.3% for PCs. From 2020, all PCs were treated with pathogen reduction technology, and no inventory stock-out was reported. The lowest PC expiry rate (0.2%) was observed after the implementation of the software for blood processing and PC stock management. The deployment of this software also improved plasma recovery: on average, an extra plasma volume of 9 mL was collected per donation in 2023 compared to 2015. A survey confirmed staff satisfaction.

conclusionThe progressive implementation of automated and software-based solutions was key to increasing efficiencies in BTBA. This enabled the optimization of blood processing by maximizing productivity, enhancing traceability, reducing overproduction and wastage and increasing the yield of recovered plasma, while ensuring blood product safety and staff satisfaction.

Indexed as

Blood BanksTissue BanksHumansRetrospective StudiesSpainblood banking improvementpathogen reduction technologyproduction algorithmproductivitytraceabilitywhole‐blood processing

Identifiers

PMID39442933
PMCPMC11753821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.