Evidence map›Paper›PMID 39442792›Full record

ArticleThe Journal of pediatrics2025

Adverse Childhood Experiences and Socioemotional Outcomes of Children Born Very Preterm.

Callie L Bishop, Rachel E Lean, Tara A Smyser, Christopher D Smyser, Cynthia E Rogers

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Callie L BishopDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO.
Rachel E LeanDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO. Electronic address: rachel.lean@wustl.edu.
Tara A SmyserDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO.
Christopher D SmyserDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO; Department of Radiology, Washington University School of Medicine, St. Louis, MO; Department of Neurology, Washington University School of Medicine, St. Louis, MO.
Cynthia E RogersDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
Trajectories of Cortico-Cerebellar Connectivity, Social Competence, and Internalizing Symptoms in Adolescents Born Very PretermR37MH113570 · NIMH · WASHINGTON UNIVERSITY · PI CYNTHIA Elise ROGERS, Christopher Daniel Smyser · 2022 to 2026
$3.8M
THE PRETERM BEHAVIORAL PHENOTYPE: TRAJECTORIES OF PSYCHOPATHOLOGY & CHANGES IN CEREBRAL CONNECTIVITYR01MH113570 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE, SMYSER, CHRISTOPHER DANIEL · 2017 to 2021
$3.1M
UNDERSTANDING NEUROBEHAVIORAL DEFICITS IN PRETERM INFANTS THROUGH IMAGINGR01HD057098 · NICHD · WASHINGTON UNIVERSITY · PI INDER, TERRIE E, NEIL, JEFFREY J. · 2008 to 2012
$2.9M
Investigating Links Between Dysfunctional Parenting and Infant Brain Connectivity on Development of Effortful ControlK01MH122735 · NIMH · WASHINGTON UNIVERSITY · PI LEAN, RACHEL EMMA · 2021 to 2025
$881k
PREDICTING CHILDHOOD OUTCOMES IN PRETERM INFANTS USING CEREBRAL CONNECTIVITYK02NS089852 · NINDS · WASHINGTON UNIVERSITY · PI SMYSER, CHRISTOPHER DANIEL · 2014 to 2018
$848k
PREDICTING PRESCHOOL PSYCHOPATHOLOGY WITH BRAIN CONNECTIVITY IN PRETERM NEONATESK23MH105179 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE · 2015 to 2018
$705k
NCATS NIH HHS UL1 TR000448NICHD NIH HHS P50 HD103525NICHD NIH HHS R01 HD057098NIMH NIH HHS K01 MH122735NIMH NIH HHS K23 MH105179NIMH NIH HHS R01 MH113570NIMH NIH HHS R37 MH113570NINDS NIH HHS K02 NS089852
6 · The paper itself

Abstract

objectiveTo examine whether adverse childhood experiences (ACEs) confer risk for socioemotional problems in children born very preterm (VPT). STUDY

designAs part of a longitudinal study, 96 infants born VPT at 23-30 weeks of gestation were recruited from a level III neonatal intensive care unit and underwent follow-up at ages 2 and 5 years. Eighty-three full-term (FT) (37-41 weeks gestation) children were recruited from an adjoining obstetric service and the local community. ACEs were assessed with the Child Life Events Scale at age 2 and Preschool Age Psychiatric Assessment at age 5. At age 5, internalizing, externalizing, and attention deficit hyperactivity disorder (ADHD) symptoms were assessed with the Child Behavior Checklist and Conner's Rating Scale-Revised, respectively. Covariates including socioeconomic disadvantage, maternal distress, and parent ADHD symptoms were assessed at the 2- and/or 5-year follow-up. Mediation and moderation analysis, accounting for family clustering, examined associations between birth group, ACEs, and socioemotional outcomes.

resultsAfter covariate adjustment, children born VPT experienced more ACEs (P < .001), particularly medical ACEs (P < .01), and had worse ADHD and internalizing outcomes (P < .05) than full-term children. ACEs mediated the association between birth group and ADHD outcomes (95% CI, 0.11-4.08). There was no evidence of mediation for internalizing outcomes. Higher parent ADHD symptoms (P < .001) and maternal distress (P < .05) were associated with poorer internalizing outcomes.

conclusionsScreening for childhood ACEs should be embedded in the follow-up care of children born VPT and their families. Strategies to screen for and address parent psychosocial functioning may be important to support children's socioemotional development.

Indexed as

Adverse Childhood ExperiencesInfant, Extremely PrematureAttention Deficit Disorder with HyperactivityChild, PreschoolFemaleFollow-Up StudiesHumansInfant, NewbornLongitudinal StudiesMaleprematuritypsychopathologystresstrauma

Identifiers

PMID39442792
PMCPMC11851865

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.