Evidence map›Paper›PMID 39442753›Full record

ReviewThe Journal of molecular diagnostics : JMD2025

Considerations for Severe Acute Respiratory Syndrome Coronavirus 2 Genomic Surveillance: A Joint Consensus Recommendation of the Association for Molecular Pathology and Association of Public Health Laboratories.

Julie W Hirschhorn, N Esther Babady, Allen Bateman, Heather M Blankenship, Jennifer Dien Bard, Kelsey Florek, Paige M K Larkin, Marie-Claire Rowlinson, Kelly Wroblewski, Donna M Wolk

Erratum issuedAbstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of molecular diagnostics : JMD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Julie W HirschhornThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina; Diagnostic Medicine Institute, Geisinger, Danville, Pennsylvania; Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania. Electronic address: jhirschhorn@geisinger.edu.
N Esther BabadyThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Department of Pathology and Laboratory Medicine and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Allen BatemanThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Wisconsin State Laboratory of Hygiene, Madison, Wisconsin.
Heather M BlankenshipThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Genomics Section, Division of Infectious Disease, Michigan Department of Health and Human Services, Lansing, Michigan.
Jennifer Dien BardThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.
Kelsey FlorekThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Wisconsin State Laboratory of Hygiene, Madison, Wisconsin.
Paige M K LarkinThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Department of Pathology, NorthShore University HealthSystem, Evanston, Illinois.
Marie-Claire RowlinsonThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Wadsworth Center Bacterial Diseases Laboratory, New York State Department of Health, Albany, New York; Bureau of Public Health Laboratories, Florida Department of Health, Jacksonville, Florida.
Kelly WroblewskiThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Association of Public Health Laboratories, Silver Spring, Maryland.
Donna M WolkThe SARS-CoV-2 Whole Genome Sequencing Working Group of the Association for Molecular Pathology, Rockville, Maryland; Diagnostic Medicine Institute, Geisinger, Danville, Pennsylvania; Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Next-generation sequencing (NGS) has applications in research, epidemiology, oncology, and infectious disease diagnostics. Wide variability exists in NGS wet laboratory techniques and dry laboratory analytical considerations. Thus, many questions remain unanswered when NGS methods are implemented in laboratories for infectious disease testing. Although this review is not intended to answer all questions, the most pressing questions from a public health and clinical hospital-based laboratory perspective will be addressed. The authors of this review are laboratory professionals who perform and interpret severe acute respiratory syndrome coronavirus 2 NGS results. Considerations for pre-analytical, analytical, and postanalytical NGS will be explored. This review highlights challenges for molecular laboratory professionals considering adopting or expanding NGS methods.

Indexed as

COVID-19High-Throughput Nucleotide SequencingSARS-CoV-2Genome, ViralGenomicsHumansLaboratoriesPathology, MolecularPublic Health

Identifiers

PMID39442753
PMCPMC11702284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.