Evidence map›Paper›PMID 39442130›Full record

ReviewArquivos brasileiros de cardiologia2024

Cardiomyopathy in Children and Adolescents in the Era of Precision Medicine.

Ana Flávia Mallheiros Torbey, Raquel Germer Toja Couto, Aurea Grippa, Eduarda Corrêa Maia, Sara Aimée Miranda, Marcos Adriano Cardoso Dos Santos, Elion Tavares Peres, Olimpio Patrick Silva Costa, Everton Mattos de Oliveira, Evandro Tinoco Mesquita

Abstract readReview
In one paragraph

Review in Arquivos brasileiros de cardiologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Flávia Mallheiros TorbeyUniversidade Federal Fluminense, Niterói, RJ - Brasil.ORCID 0000-0001-7935-7966
Raquel Germer Toja CoutoUniversidade Federal Fluminense Hospital Universitário Antônio Pedro (EBSERH), Niterói, RJ - Brasil.
Aurea GrippaUniversidade Federal Fluminense, Niterói, RJ - Brasil.ORCID 0000-0002-5969-8226
Eduarda Corrêa MaiaUniversidade Federal Fluminense, Niterói, RJ - Brasil.ORCID 0000-0001-9011-7779
Sara Aimée MirandaUniversidade Federal Fluminense, Niterói, RJ - Brasil.
Marcos Adriano Cardoso Dos SantosUniversidade Federal Fluminense, Niterói, RJ - Brasil.
Elion Tavares PeresUniversidade Federal Fluminense, Niterói, RJ - Brasil.
Olimpio Patrick Silva CostaUniversidade Federal Fluminense, Niterói, RJ - Brasil.ORCID 0000-0001-7012-1252
Everton Mattos de OliveiraUniversidade Federal Fluminense, Niterói, RJ - Brasil.ORCID 0000-0002-7875-4676
Evandro Tinoco MesquitaUniversidade Federal Fluminense, Niterói, RJ - Brasil.ORCID 0000-0002-7452-3870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In childhood and adolescence, cardiomyopathies have their own characteristics and are an important cause of heart failure, arrhythmias, sudden death, and indication for heart transplantation. Diagnosis is a challenge in daily practice due to its varied clinical presentation, heterogeneous etiologies, and limited knowledge of tools related to clinical and molecular genetics. However, it is essential to recognize the different phenotypes and prioritize the search for the etiology. Recent advances in precision medicine have made molecular diagnosis accessible, which makes it possible to individualize therapeutic approaches, stratify the prognosis, and identify individuals in the family who are at risk of developing the disease. The objective of this review is to emphasize the particularities of cardiomyopathies in pediatrics and how the individualized approach impacts the therapy and prognosis of the patient. Through a systematized approach, the five-stage protocol used in our service is presented. These stages bring together clinical evaluation for determining the morphofunctional phenotype, identification of etiology, classification, establishment of prognosis, and the search for personalized therapies.

Indexed as

CardiomyopathiesPrecision MedicineAdolescentChildHumansPhenotypePrognosis

Identifiers

PMID39442130
PMCPMC11634207

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.