Evidence map›Paper›PMID 39441815›Full record

ArticlePloS one2024

Age-related changes in gait, balance, and strength parameters: A cross-sectional study.

Asghar Rezaei, Sandesh G Bhat, Chih-Hsiu Cheng, Robert J Pignolo, Lichun Lu, Kenton R Kaufman

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
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  4. Article
  5. Functional, molecular, and digital measurements of biological age.The Journal of clinical investigation · 2026
    Review
  6. Article
  7. Article
  8. Article
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  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Development and validation of the mobility in middle-age questionnaire.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Asghar RezaeiDepartment of Orthopedic Surgery, Division of Orthopedic Research, Mayo Clinic, Rochester, MN, United States of America.
Sandesh G BhatDepartment of Orthopedic Surgery, Division of Orthopedic Research, Mayo Clinic, Rochester, MN, United States of America.ORCID 0000-0002-8989-0235
Chih-Hsiu ChengSchool of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Linkou, Taoyuan, Taiwan.
Robert J PignoloDepartment of Medicine, Divisions of Geriatric Medicine and Gerontology, Endocrinology and Hospital Internal Medicine, and the Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, United States of America.
Lichun LuDepartment of Orthopedic Surgery, Division of Orthopedic Research, Mayo Clinic, Rochester, MN, United States of America.
Kenton R KaufmanDepartment of Orthopedic Surgery, Division of Orthopedic Research, Mayo Clinic, Rochester, MN, United States of America.

Funding

A patient-specific computational technique to predict spine injury risks associated with physical activitiesK25AG068368 · NIA · MAYO CLINIC ROCHESTER · PI REZAEI, ASGHAR · 2021 to 2025
$737k
NIA NIH HHS K25 AG068368
6 · The paper itself

Abstract

backgroundLongevity is increasing worldwide due to improvements in healthcare and living standards. Aging is often associated with disability and multiple health concerns. To address these challenges, effective interventions are essential. This study investigated potential age-related declines in gait, balance, and strength. We also sought to assess any relationships between these three parameters and explore potential differences between women and men.

methodsHealthy individuals over 50 years of age were recruited for this cross-sectional study. Upper extremity (grip) strength and lower extremity (knee) strength of the dominant side were measured. Static balance was performed on the force plate in different situations each for 30 seconds: bilateral stance with eyes open, bilateral stance with eyes closed, as well as dominant leg and non-dominant leg unilateral stance with eyes open. Gait was measured during level walking using an optical motion capture system. Additionally, the dynamic stability margin (DSM) was calculated for the level walking trials.

resultsThe study results indicated that gait parameters were not significantly affected by age (p≥0.12), while knee and grip strength, along with several balance parameters, showed a significant decline with age. All individuals were able to maintain their bipedal balance, but their center of pressure movement increased significantly by age (p≤0.028). Z-scores were calculated to compare significant age parameters. Unipedal stance time was found to be the most affected by age compared to other contributing factors (p≤0.001). The duration of unipedal balance showed the most significant change per decade (non-dominant: -0.62 SDs; dominant: -0.53 SDs), while strength measures exhibited the lowest amount of change per decade (grip strength: -0.34 SDs; knee strength: -0.26 SDs). Sex differences were observed exclusively in strength parameters, with no discernible impact on the decline in balance parameters.

conclusionsThese findings suggest that the duration of unipedal stance can serve as a reliable and gender-independent measure of neuromuscular aging for both elderly male and female subjects.

Indexed as

AgingGaitPostural BalanceAgedAged, 80 and overCross-Sectional StudiesFemaleHand StrengthHumansMaleMiddle AgedMuscle Strength

Identifiers

PMID39441815
PMCPMC11498712

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.