Evidence map›Paper›PMID 39441712›Full record

ArticleJournal of pediatric psychology2025

Supporting emotion regulation in children on the autism spectrum: co-developing a digital mental health application for school-based settings with community partners.

Isha Kaur, Rima Kamel, Evan Sultanik, Jessica Tan, Carla A Mazefsky, Lauren Brookman-Frazee, James C McPartland, Matthew S Goodwin, Jeffrey Pennington, Rinad S Beidas and 2 more

Abstract read
In one paragraph

Article in Journal of pediatric psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review and Developmental Model: Early Childhood Emotion Regulation and Co-Regulation in Autism.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Isha KaurPenn Center for Mental Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Rima KamelPenn Center for Mental Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Evan SultanikAlevio LLC, Philadelphia, PA, USA.
Jessica TanSchool of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Carla A MazefskyDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Lauren Brookman-FrazeeDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
James C McPartlandYale Child Study Center, Yale University, New Haven, CT, USA.
Matthew S GoodwinBouvé College of Health Sciences, Northeastern University, Boston, MA, USA.
Jeffrey PenningtonChildren's Hospital of Philadelphia Research Institute, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Rinad S BeidasDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
David S MandellPenn Center for Mental Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Heather J NuskePenn Center for Mental Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-6618-3768

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Reducing Challenging Behaviors In Children With Autism Through Digital HealthK01MH120509 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI NUSKE, HEATHER J · 2020 to 2024
$773k
NCATS NIH HHS UL1 TR001863NIMH NIH HHS K01 MH120509NIMH NIH HHS K01MH120509
6 · The paper itself

Abstract

objectiveKeepCalm is a digital mental health application, co-designed with community partners, that incorporates wearable biosensing with support for teams to address challenging behaviors and emotion dysregulation in children on the autism spectrum.

methodsWe followed a user-centered design framework. Before app development, we conducted design workshops, needs assessment interviews, a systematic review, and created an Expert Advisory Board. Once we had a working prototype, we recruited 73 participants to test and help improve the app across five testing cycles.

resultsParticipants rated the app across testing cycles as highly acceptable, appropriate, feasible, and with good usability. Qualitative data indicated that KeepCalm helped teachers (a) be aware of students' previously unrealized triggers, especially for nonspeaking students; (b) prevent behavioral episodes; (c) communicate with parents about behaviors/strategies; and (d) equipped parents with knowledge of strategies to use at home. We learned that in order to make the app acceptable and appropriate we needed to make the app enjoyable/easy to use and to focus development on novel features that augment teachers' skills (e.g., behavioral pattern and stress detection). We also learned about the importance of maximizing feasibility, through in-person app training/support especially regarding the wearable devices, and the importance of having aides involved.

conclusionOur findings have informed plans for wider-scale feasibility testing so that we may examine the determinants of implementation to inform adaptations and refinement, and gather preliminary efficacy data on KeepCalm's impact on reducing challenging behaviors and supporting emotion regulation in students on the autism spectrum.

Indexed as

Autism Spectrum DisorderEmotional RegulationMobile ApplicationsSchool Health ServicesChildFemaleHumansMaleWearable Electronic Devicesautism spectrumbehavior problemscardiologyeHealth/mHealthevidence-based practicepreschool childrenschool-age children

Identifiers

PMID39441712
PMCPMC11753873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.