Evidence map›Paper›PMID 39441631›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

FlaG competes with FliS-flagellin complexes for access to FlhA in the flagellar T3SS to control

Alexis A Waller, Deborah A Ribardo, David R Hendrixson

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. CRISPRi Screening Identifies EssentialInternational journal of molecular sciences · 2026
    Article
  2. AProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Impact of flagellar filament length onJournal of bacteriology · 2025
    Article
  4. FliO is an evolutionarily conserved yet diversified core component of the bacterial flagellar type III secretion system.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. ThemBio · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexis A WallerDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9048.ORCID 0000-0002-1435-7911
Deborah A RibardoDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9048.
David R HendrixsonDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9048.ORCID 0000-0001-8496-2466

Funding

Flagellar Motor Biogenesis in Polarly-Flagellated Bacterial PathogensR01AI065539 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI DAVID R HENDRIXSON · 2006 to 2026
$9.2M
Control of Flagellar Filament Length by FlaG in Polarly-Flagellated Bacterial PathogensR21AI159140 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI HENDRIXSON, DAVID R · 2021 to 2022
$451k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI065539HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI159140NIAID NIH HHS R01 AI065539NIAID NIH HHS R21 AI159140
6 · The paper itself

Abstract

Bacteria power rotation of an extracellular flagellar filament for swimming motility. Thousands of flagellin subunits compose the flagellar filament, which extends several microns from the bacterial surface. It is unclear whether bacteria actively control filament length. Many polarly flagellated bacteria produce shorter flagellar filaments than peritrichous bacteria, and FlaG has been reported to limit flagellar filament length in polar flagellates. However, a mechanism for how FlaG may function is unknown. We observed that deletion of

Indexed as

Bacterial ProteinsCampylobacter jejuniFlagellaFlagellinType III Secretion SystemsMembrane ProteinsVibrio choleraeBacterial ProteinsFlagellinFlhA protein, BacteriaFliS protein, BacteriaMembrane ProteinsType III Secretion SystemsCampylobacter jejuniFlaGflagellar filament lengthFlhAFliS

Identifiers

PMID39441631
PMCPMC11536152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.