Evidence map›Paper›PMID 39441368›Full record

ArticleSurgical case reports2024

An aggressive gastric CIC-DUX4 sarcoma surgically resected with multivisceral organs: a case report.

Mizuki Koba, Atsushi Takeno, Hiroko Hasegawa, Ryotaro Sakamori, Rei Higashiura, Masaaki Yamamoto, Shinji Tokuyama, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi and 8 more

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In one paragraph

Article in Surgical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Mizuki KobaDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Atsushi TakenoDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan. atakeno1008@me.com.ORCID http://orcid.org/0000-0003-2003-2942
Hiroko HasegawaDepartment of Gastroenterology and Hepatology, NHO Osaka National Hospital, Osaka, Japan.
Ryotaro SakamoriDepartment of Gastroenterology and Hepatology, NHO Osaka National Hospital, Osaka, Japan.
Rei HigashiuraDepartment of Gastroenterology and Hepatology, NHO Osaka National Hospital, Osaka, Japan.
Masaaki YamamotoDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Shinji TokuyamaDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Reishi ToshiyamaDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Kenji KawaiDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Yusuke TakahashiDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Kenji SakaiDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Naoki HamaDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Kunihito GotohDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Takeshi KatoDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.
Yumiko HiroseDepartment of Central Laboratory and Surgical Pathology, NHO Osaka National Hospital, Osaka, Japan.
Kiyoshi MoriDepartment of Central Laboratory and Surgical Pathology, NHO Osaka National Hospital, Osaka, Japan.
Masayuki ManoDepartment of Central Laboratory and Surgical Pathology, NHO Osaka National Hospital, Osaka, Japan.
Motohiro HiraoDepartment of Surgery, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCapicua transcriptional repressor-double homeobox 4 sarcoma (CDS) is a rare and aggressive malignant soft tissue tumor that typically arises within the soft tissues. We report an exceptionally rare case of a gastric CDS successfully resected despite its extensive invasion into surrounding organs. CASE PRESENTATION: A 48-year-old male presented with a progressively enlarging abdominal mass. Upper gastrointestinal endoscopy revealed a large ulcerative tumor on the posterior gastric wall. Biopsy results initially suggested a neuroendocrine cell carcinoma. Contrast-enhanced computed tomography showed a 20 cm tumor protruding from the posterior stomach wall, directly invading the pancreas and colon. We performed a multivisceral resection (stomach, pancreatic tail, spleen, and transverse colon) achieving an R0 resection. Pathological examination of the permanent specimen revealed small round cells with high nuclear-to-cytoplasmic ratios. Immunohistochemical staining confirmed the diagnosis of CDS. The patient recovered well and was discharged on postoperative day 33.

conclusionsThis case report describes the first detailed account of a surgically resected aggressive CDS originating from the stomach.

Indexed as

CIC-DUX4 sarcomaStomachSurgical resection

Identifiers

PMID39441368
PMCPMC11499562

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.