Evidence map›Paper›PMID 39441228›Full record

ArticleJournal of ophthalmic inflammation and infection2024

Foscarnet eyedrops for the treatment of refractory herpetic keratitis.

Caroline C Awh, Austen N Knapp, Jeffrey M Goshe, Craig W See, Careen Y Lowder

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caroline C AwhCole Eye Institute, Cleveland Clinic, i-32, 9500, Euclid Ave, Cleveland, OH, 44195, USA.
Austen N KnappCole Eye Institute, Cleveland Clinic, i-32, 9500, Euclid Ave, Cleveland, OH, 44195, USA.
Jeffrey M GosheCole Eye Institute, Cleveland Clinic, i-32, 9500, Euclid Ave, Cleveland, OH, 44195, USA.
Craig W SeeCole Eye Institute, Cleveland Clinic, i-32, 9500, Euclid Ave, Cleveland, OH, 44195, USA.
Careen Y LowderCole Eye Institute, Cleveland Clinic, i-32, 9500, Euclid Ave, Cleveland, OH, 44195, USA. lowderc@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this case series is to describe the clinical course of patients receiving foscarnet eyedrops for the treatment of refractory herpetic keratitis. OBSERVATIONS: Six patients diagnosed with herpetic keratitis were treated with foscarnet 24 mg/mL (2.4%) eyedrops with resulting improvement in keratitis.

conclusionTopical foscarnet may be a safe and effective treatment for herpetic keratitis in conjunction with, or as an alternative to, conventional antiviral therapy. This is an off-label use of foscarnet.

Identifiers

PMID39441228
PMCPMC11499480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.