Evidence map›Paper›PMID 39441163›Full record

Observational studyLa Tunisie medicale2024

Dhouha Nefzi, Lotfi Chaabani, Arij Jouini, Nesrine Abroug, Imen Ksiaa, Moncef Khairallah

Abstract readObservational StudyEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Observational study in La Tunisie medicale, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dhouha NefziOphthalmology Department, Kasserine Regional Hospital. Faculty of Medicine of Sousse, University of Sousse, Tunisia.
Lotfi ChaabaniOphthalmology Department, Kasserine Regional Hospital. Faculty of Medicine of Sousse, University of Sousse, Tunisia.
Arij JouiniOphthalmology Department, Kasserine Regional Hospital. Faculty of Medicine of Sousse, University of Sousse, Tunisia.
Nesrine AbrougOphthalmology Department, Fattouma Bourguiba University Hospital, Monastir. Faculty of Medicine of Monastir, University of Monastir, Tunisia.
Imen KsiaaOphthalmology Department, Fattouma Bourguiba University Hospital, Monastir. Faculty of Medicine of Monastir, University of Monastir, Tunisia.
Moncef KhairallahOphthalmology Department, Fattouma Bourguiba University Hospital, Monastir. Faculty of Medicine of Monastir, University of Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimto describe and analyze peripapillary microvascular changes in eyes with optic neuropathies using optical coherence tomography angiography (OCTA).

methodsIn this cross-sectional observational study, 63 eyes of 48 patients with different causes of optic neuropathy and 36 healthy control eyes were evaluated by optical coherence tomography (OCT) and OCTA (Topcon DRI OCT; Triton) between January 2018 and December 2018 at the Fattouma Bourguiba ophthalmology department in Monastir.

resultsVascular changes were more frequent in acute non arteritic anterior ischemic optic neuropathy (NAION) than in optic neuritis. Eyes with optic atrophy had capillary rarefaction corresponding to the area of thinning of the peripapillary optic fiber layer (RNFL). The peripapillary vascular density (PVD) was lower (p=0.036) in case of optic atrophy compared to normal eyes. For non arteritic ischemic optic neuropathy and for chronic retrobulbar optic neuritis (NORB), a positive correlation between visual acuity and PVD was observed (p<0.05). An inversely proportional correlation between the PVD and the duration of evolution was noted. In the multivariate study, high blood pressure was a systemic factor correlated with peripapillary microvascular damages.

conclusionOCTA showed a reduction in PVD and greater vascular changes in acute non-arteritic ischemic optic neuropathy than in edematous optic neuritis. At the atrophic stage, the PVD was reduced. Hypertension was an independent factor correlated with peripapillary microvascular damages.

Indexed as

Tomography, Optical CoherenceAdultAgedCase-Control StudiesCross-Sectional StudiesFemaleFluorescein AngiographyHumansMaleMiddle AgedOptic DiskOptic Nerve DiseasesOptic NeuritisOptic Neuropathy, IschemicRetinal VesselsVisual AcuityangiographyEyeoptical coherence tomographyoptic neuropathy

Identifiers

PMID39441163
PMCPMC11574376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.