ArticleAmerican journal of respiratory and critical care medicine2025
Serum Immunoglobulin G Levels Are Associated with Risk for Exacerbations: An Analysis of SPIROMICS.
Abstract read
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Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Low levels of IgG2 and pneumococcal antibodies as predictors of benefit from IgG replacement in IgG subclass deficiency.Journal of human immunity · 2026Article
- Associations of serum and bronchoalveolar immunoglobulins with lung microbiota diversity, B-cell memory phenotypes, and COPD morbidity and exacerbations.Respiratory research · 2025Observational
- The Impact of Comorbidities on Serum IgG Levels and Exacerbation Risk in Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2025Article
- Lower IgG Levels Increased Exacerbation Risk in Chronic Obstructive Pulmonary Disease: New Insights for Clinical Practice.American journal of respiratory and critical care medicine · 2025Article
- Reply to ChenAmerican journal of respiratory and critical care medicine · 2025Article
- Best in Class: IgG as a Treatable Trait for Exacerbation Prevention in Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2025Article
- Dietary selenium supplementation: its impact on growth, microbiota, antioxidant capacity, and immunity in Inner Mongolian cashmere goats.Frontiers in veterinary science · 2025Article
- Reduced quantity and function of pneumococcal antibodies are associated with exacerbations of COPD in SPIROMICS.Clinical immunology (Orlando, Fla.) · 2023Article
Corrections and comments
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Authors and funding
29 authors.
Michael BurnimDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0001-7720-2020
Nirupama PutchaDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-0688-1836
David LaFonUniversity of Alabama Birmingham Marnix E. Heersink School of Medicine, Birmingham, Alabama.ORCID 0000-0001-5174-1931
Han WooDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Antoine AzarDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-0782-9084
Lars GroenkeCSL Behring GmbH, Marburg, Germany.
Martin StampfliCSL Behring GmbH, Marburg, Germany.ORCID 0000-0003-4918-5889
Alexander SchaubCSL Behring GmbH, Marburg, Germany.
Ashraf FawzyDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-6089-366X
Aparna BalasubramanianDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-1854-6672
Neal FedarkoDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0001-6055-6279
Christopher B CooperUniversity of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California.ORCID 0000-0002-6314-0903
Russell P BowlerNational Jewish Health, Denver, Colorado.ORCID 0000-0003-4651-363X
Alejandro ComellasUniversity of Iowa School of Medicine, Iowa City, Iowa.ORCID 0000-0003-1521-7520
Jerry A KrishnanUniversity of Illinois Chicago, Chicago, Illinois.ORCID 0000-0001-5525-4778
MeiLan K HanUniversity of Michigan School of Medicine, Ann Arbor, Michigan.ORCID 0000-0002-9095-4419
David CouperUniversity of North Carolina Marsico Lung Institute, Chapel Hill, North Carolina.ORCID 0000-0002-4313-9235
Stephen P PetersWake Forest University School of Medicine, Winston-Salem, North Carolina.
M Bradley DrummondUniversity of North Carolina Marsico Lung Institute, Chapel Hill, North Carolina.ORCID 0000-0002-6968-4610
Wanda O'NealUniversity of North Carolina Marsico Lung Institute, Chapel Hill, North Carolina.ORCID 0000-0003-2412-5943
Robert PaineUniversity of Utah School of Medicine, Salt Lake City, Utah.ORCID 0000-0002-4511-4437
Gerard CrinerTemple University School of Medicine, Philadelphia, Pennsylvania.ORCID 0000-0003-1267-3483
Fernando J MartinezCornell University School of Medicine, New York, New York.ORCID 0000-0002-2412-3182
Jeffrey L CurtisUniversity of Michigan School of Medicine, Ann Arbor, Michigan.ORCID 0000-0001-5191-4847
Graham BarrColumbia University Medical Center, New York, New York; and.ORCID 0000-0002-0743-2303
Yvonne J HuangUniversity of Michigan School of Medicine, Ann Arbor, Michigan.ORCID 0000-0002-7497-6597
Prescott WoodruffUniversity of California, San Francisco, School of Medicine, San Francisco, California.ORCID 0000-0003-3176-0603
Mark DransfieldUniversity of Alabama Birmingham Marnix E. Heersink School of Medicine, Birmingham, Alabama.ORCID 0000-0002-9207-1820
Nadia N HanselDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-8740-9751
Funding
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5MMULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3MSPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9MUnderstanding the Origins of Early COPDR01HL144718 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CURTIS, JEFFREY LOUIS, HAN, MEILAN K · 2020 to 2024
$11.3MSPIROMICS GIC SupportU24HL141762 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J, O'NEAL, WANDA K · 2018 to 2022
$7.2MNHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900014CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268200900020CNHLBI NIH HHS R01 HL144718NHLBI NIH HHS T 32 HL 007534NHLBI NIH HHS U01 HL137880NHLBI NIH HHS U24 HL141762NIEHS NIH HHS P30 ES005605
Abstract
PubMed holds no abstract for this paper.
Indexed as
IgG DeficiencyImmunoglobulin GPulmonary Disease, Chronic ObstructiveAgedBiomarkersDisease ProgressionFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsSmokingBiomarkersImmunoglobulin GCOPDexacerbationimmunoglobulin Grisk factor
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Textmetadata
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.