Evidence map›Paper›PMID 39440994›Full record

ArticleJournal of glaucoma2025

Socioeconomic and Racial Disparities in Primary Open Angle Glaucoma in the United States.

Carolyn S Downs, Paul J Percelay, Brandon Williams, Patricia J Goedecke, Jess M Wesberry, Nawajes Mandal

Abstract read
In one paragraph

Article in Journal of glaucoma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carolyn S DownsDepartment of Ophthalmology, Hamilton Eye Institute.
Paul J PercelayDepartment of Ophthalmology, University of Missouri, Columbia, MO.
Brandon WilliamsDepartment of Ophthalmology, Hamilton Eye Institute.
Patricia J GoedeckeBERD: Biostatistics, Epidemiology and Research Design.
Jess M WesberryDepartment of Ophthalmology, Hamilton Eye Institute.
Nawajes MandalDepartment of Ophthalmology, Hamilton Eye Institute.

Funding

Ceramides and Sphingolipids as Predictors of Incident DysglycemiaR01DK128129 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI DAGOGO-JACK, M.D., D.SC., SAMUEL, MANDAL, NAWAJES · 2021 to 2024
$2.0M
Sphingolipids and their Impact in Corneal Wound HealingR01EY031316 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KARAMICHOS, DIMITRIOS, MANDAL, NAWAJES · 2020 to 2023
$1.8M
BLRD VA I01 BX004893NEI NIH HHS R01 EY031316NIDDK NIH HHS R01 DK128129
6 · The paper itself

Abstract

PRÉCIS: Socioeconomic status is a potentially significant, although difficult to isolate, factor in determining glaucoma severity. PURPOSE: To analyze the level of glaucoma severity (mild, moderate, or severe) based on demographic factors, including age, gender, ethnicity, insurance profile, and zip code, and to use this data to extrapolate the effect of socioeconomic status (SES) and race on glaucoma severity at the community level in Memphis, TN. PATIENTS AND

methodsTotally, 2913 patients from a tertiary care center with 3 clinic locations in Memphis, TN who had been given the diagnosis of primary open angle glaucoma (POAG) through use of the ICD-10 codes for mild (H40.1111, H40.1121, H40.1131), moderate (H40.1112, H40.1122, H40.1132), and severe (H40.1113, H40.1123, H40.1133) POAG between January 2016 and July 2021 were included in this study. Diagnoses were made after a complete glaucoma workup consisting of Snellen visual acuity, applanation IOP measurement, gonioscopy, automated Humphreys visual fields (10-2 and 24-2), and optic nerve OCT. Demographic information, including age, gender, ethnicity, insurance profile, and zip code, was also collected with disease severity for each patient. SES was approximated using zip code-level census poverty data and insurance profiles. Statistical analyses were performed, including descriptive, multivariable ordinal logistic modeling, and stepwise multivariable linear modeling.

resultsGlaucoma severity was shown to increase with poverty rate (OR=1.089, P <0.0071), age (OR=1.030, P <0.0001), male sex (OR=1.374, P <0.0001), and Black race (OR=1.896, P <0.0001). Severity was shown to be decreased in patients with private insurance compared with Medicare (OR=0.895, P <0.093) and those from Shelby County compared with other counties (OR=0.703, P <0.0001).

conclusionsOur findings indicate that worsening glaucoma severity was associated with higher poverty rates in our patient population. However, isolating socioeconomic status (SES) as an independent factor influencing the incidence and severity of glaucoma remains challenging, given the strong correlation between race and SES.

Indexed as

Glaucoma, Open-AngleHealth Status DisparitiesIntraocular PressureRacial GroupsSocial ClassAgedAged, 80 and overFemaleGonioscopyHumansMaleMiddle AgedRetrospective StudiesSocioeconomic FactorsUnited StatesVisual Acuity

Identifiers

PMID39440994
PMCPMC12883170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.