Evidence map›Paper›PMID 39440706›Full record

SynthesisCancer medicine2024

Advancements in hydrogel-based embolic agents: Categorized by therapeutic mechanisms.

Shenbo Zhang, Rui Lv, Zhe Zhang, Zhiwei Wang, Zhengyu Jin

Abstract readSystematic Review
In one paragraph

Synthesis in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shenbo ZhangDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.ORCID https://orcid.org/0009-0004-7879-0118
Rui LvDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Zhe ZhangDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Zhiwei WangDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Zhengyu JinDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Funding

Key Programme 22232006National High-Level Hospital Clinical Research Funding 2022-PUMCH-B-68
6 · The paper itself

Abstract

backgroundTranscatheter arterial embolization (TAE) is a crucial technique in interventional radiology. Hydrogel-based embolic agents show promise due to their phase transition and drug-loading capabilities. However, existing categorizations of these agents are confusing.

aimsThis review tackles the challenge of categorizing hydrogel-based embolic agents based on their therapeutic mechanisms, including transportation, accumulation, interaction, and elimination. It also addresses current challenges and controversies in the field while highlighting future directions for hydrogel-based embolicagents. MATERIALS AND

methodsWe conducted a systematic review of papers published in PUBMED from 2004 to 2024, focusing primarily on preclinical trials.

resultsVarious kinds of hydrogel embolic agents were introduced according to their therapeutic mechanisms. DISCUSSION: Most hydrogel embolic agents were specifically designed for effective accumulation and interaction. Recent advancement highlight the potential of multifunctional hydrogel embolic agents.

conclusionThis new categorizations provided valuable insights into hydrogel embolic agents, potentially guiding material scientists and interventional radiologists in the development of novel hydrogel embolic agents in transarterial embolization.

Indexed as

Embolization, TherapeuticHydrogelsAnimalsHumansHydrogelsembolic agentshydrogelsinstrumentationinterventional radiologytherapeutic embolization

Identifiers

PMID39440706
PMCPMC11497111

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.