Evidence map›Paper›PMID 39440220›Full record

ArticleJournal of clinical and translational hepatology2024

Development and Validation of a New Prognostic Model for Predicting Survival Outcomes in Patients with Acute-on-chronic Liver Failure.

Wende Li, Wanshu Liu, Yihui Rong, Dongze Li, Bing Zhu, Shaobo Yang, Shidong Sun, Shaoli You, Yu Chen, Jun Li

Abstract read
In one paragraph

Article in Journal of clinical and translational hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Development and validation of a prognostic model for acute-on-chronic liver failure.Frontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wende LiDepartment of Infection and Liver Diseases, Peking University International Hospital, Beijing, China.
Wanshu LiuDepartment of Hepatology Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Yihui RongDepartment of Infection and Liver Diseases, Peking University International Hospital, Beijing, China.
Dongze LiDepartment of Hepatology Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Bing ZhuDepartment of Hepatology Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Shaobo YangDepartment of Infection and Liver Diseases, Peking University International Hospital, Beijing, China.
Shidong SunDepartment of Infection and Liver Diseases, Peking University International Hospital, Beijing, China.
Shaoli YouDepartment of Hepatology Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-8689-8509
Yu ChenFourth Department of Liver Disease, Beijing Youan Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-1906-7486
Jun LiState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-7236-8088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Early determination of prognosis in patients with acute-on-chronic liver failure (ACLF) is crucial for optimizing treatment options and liver allocation. This study aimed to identify risk factors associated with ACLF and to develop new prognostic models that accurately predict patient outcomes. Methods: We retrospectively selected 1,952 hospitalized patients diagnosed with ACLF between January 2010 and June 2018. This cohort was used to develop new prognostic scores, which were subsequently validated in external groups. Results: The study included 1,386 ACLF patients and identified six independent predictors of 28-day mortality through multivariate analysis (all Conclusions: This study presents a refined prognostic model, the Model for end-stage liver disease-complication score, which accurately predicts short-term mortality in ACLF patients. This model offers a new perspective and tool for improved clinical decision-making and short-term prognostic assessment in ACLF patients.

Indexed as

ACLFAcute-on-chronic liver failureModelMortalityOutcome predictionPrognosis

Identifiers

PMID39440220
PMCPMC11491505

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.